ID   DBH_AQUAE               Reviewed;          94 AA.
AC   O67461;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; OrderedLocusNames=aq_1484.1; ORFNames=aq_1484A;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE000657; AAC07415.1; -; Genomic_DNA.
DR   PIR; C70429; C70429.
DR   RefSeq; NP_214026.1; NC_000918.1.
DR   RefSeq; WP_010880964.1; NC_000918.1.
DR   AlphaFoldDB; O67461; -.
DR   SMR; O67461; -.
DR   STRING; 224324.aq_1484a; -.
DR   EnsemblBacteria; AAC07415; AAC07415; aq_1484a.
DR   KEGG; aae:aq_1484a; -.
DR   eggNOG; COG0776; Bacteria.
DR   HOGENOM; CLU_105066_2_4_0; -.
DR   InParanoid; O67461; -.
DR   OMA; ANHLWEV; -.
DR   OrthoDB; 1847472at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..94
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104907"
SQ   SEQUENCE   94 AA;  11076 MW;  C8DD9A08D1DC0575 CRC64;
     MTKKEIAEEI YDRLIRDYNV KIQKKEVYNL VSEVFTIIQE CLLKGEKVKI SGFGTFVVKT
     RKPKKGMNIK KREIVEVPER KIVLFKPSKN FIKS