DBH_BORGP
ID DBH_BORGP Reviewed; 108 AA.
AC Q57153; Q45164; Q57235; Q662D2;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=DNA-binding protein HBbu;
GN Name=hbb; OrderedLocusNames=BG0235;
OS Borrelia garinii subsp. bavariensis (strain ATCC BAA-2496 / DSM 23469 /
OS PBi) (Borrelia bavariensis).
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=290434;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=A19S, ATCC BAA-2496 / DSM 23469 / PBi, IP89, NT29, SIKA1, SIKA2,
RC VS102, and VSBP;
RX PubMed=8995795; DOI=10.1099/00207713-47-1-1;
RA Valsangiacomo C., Balmelli T., Piffaretti J.C.;
RT "A phylogenetic analysis of Borrelia burgdorferi sensu lato based on
RT sequence information from the hbb gene, coding for a histone-like
RT protein.";
RL Int. J. Syst. Bacteriol. 47:1-10(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-2496 / DSM 23469 / PBi;
RX PubMed=15547252; DOI=10.1093/nar/gkh953;
RA Gloeckner G., Lehmann R., Romualdi A., Pradella S., Schulte-Spechtel U.,
RA Schilhabel M., Wilske B., Suehnel J., Platzer M.;
RT "Comparative analysis of the Borrelia garinii genome.";
RL Nucleic Acids Res. 32:6038-6046(2004).
CC -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC DNA to stabilize it, and thus to prevent its denaturation under extreme
CC environmental conditions. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000305}.
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DR EMBL; U48656; AAC73078.1; -; Genomic_DNA.
DR EMBL; U48657; AAC73079.1; -; Genomic_DNA.
DR EMBL; U48664; AAC73086.1; -; Genomic_DNA.
DR EMBL; U48658; AAC73080.1; -; Genomic_DNA.
DR EMBL; U48659; AAC73081.1; -; Genomic_DNA.
DR EMBL; U48660; AAC73082.1; -; Genomic_DNA.
DR EMBL; U48661; AAC73083.1; -; Genomic_DNA.
DR EMBL; U48662; AAC73084.1; -; Genomic_DNA.
DR EMBL; CP000013; AAU07089.1; -; Genomic_DNA.
DR RefSeq; WP_004793776.1; NZ_CP028872.1.
DR AlphaFoldDB; Q57153; -.
DR SMR; Q57153; -.
DR STRING; 290434.BG0235; -.
DR EnsemblBacteria; AAU07089; AAU07089; BG0235.
DR GeneID; 64198370; -.
DR GeneID; 66542419; -.
DR KEGG; bga:BG0235; -.
DR eggNOG; COG0776; Bacteria.
DR HOGENOM; CLU_105066_1_3_12; -.
DR OMA; PAHEGIN; -.
DR OrthoDB; 1847472at2; -.
DR Proteomes; UP000002276; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR Gene3D; 4.10.520.10; -; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR PANTHER; PTHR33175; PTHR33175; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; SSF47729; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA condensation; DNA-binding.
FT CHAIN 1..108
FT /note="DNA-binding protein HBbu"
FT /id="PRO_0000104920"
FT VARIANT 19..20
FT /note="SL -> FF (in strain: SIKA1 and SIKA2)"
FT VARIANT 90
FT /note="V -> I (in strain: VS102)"
SQ SEQUENCE 108 AA; 12724 MW; 4A95CE939FBEB7A5 CRC64;
MSFSRRPKIT KSDIVDQISL NIRNNNLKLE KKYIRLVIDA FFEELKGNLC LNNVIEFRSF
GTFEVRKRKG RLNARNPQTG EYVKVLDHHV AYFRPGKDLK ERVWGIKG
