ID   DBH_CAMJR               Reviewed;          98 AA.
AC   Q5HUP6; Q3MLK5;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; OrderedLocusNames=CJE0991;
OS   Campylobacter jejuni (strain RM1221).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Campylobacteraceae; Campylobacter.
OX   NCBI_TaxID=195099;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Fagerquist C.K., Miller W.G., Harden L.A., Bates A.H., Vensel W.H.,
RA   Wang G., Mandrell R.E.;
RT   "Genomic and proteomic identification of a DNA-binding protein biomarker
RT   used in the discrimination of Campylobacter species and strains by MALDI-
RT   TOF-MS.";
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RM1221;
RX   PubMed=15660156; DOI=10.1371/journal.pbio.0030015;
RA   Fouts D.E., Mongodin E.F., Mandrell R.E., Miller W.G., Rasko D.A.,
RA   Ravel J., Brinkac L.M., DeBoy R.T., Parker C.T., Daugherty S.C.,
RA   Dodson R.J., Durkin A.S., Madupu R., Sullivan S.A., Shetty J.U.,
RA   Ayodeji M.A., Shvartsbeyn A., Schatz M.C., Badger J.H., Fraser C.M.,
RA   Nelson K.E.;
RT   "Major structural differences and novel potential virulence mechanisms from
RT   the genomes of multiple Campylobacter species.";
RL   PLoS Biol. 3:72-85(2005).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY751947; AAW83337.1; -; Genomic_DNA.
DR   EMBL; CP000025; AAW35324.1; -; Genomic_DNA.
DR   RefSeq; WP_002859562.1; NC_003912.7.
DR   AlphaFoldDB; Q5HUP6; -.
DR   SMR; Q5HUP6; -.
DR   KEGG; cjr:CJE0991; -.
DR   HOGENOM; CLU_105066_3_2_7; -.
DR   OMA; PAHEGIN; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding.
FT   CHAIN           1..98
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000291774"
SQ   SEQUENCE   98 AA;  10274 MW;  E3CC1FE3BEA70333 CRC64;
     MTKADFISLV AQTAGLTKKD ATTATDAVIS TITDVLAKGD SISFIGFGTF STQERAAREA
     RVPSTGKTIK VPATRVAKFK VGKNLKEAVA KASGKKKK