ID   DBH_CAUVN               Reviewed;          92 AA.
AC   B8GX11; O87475;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; OrderedLocusNames=CCNA_02036;
OS   Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=565050;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   England J.E., Gober J.W.;
RL   Submitted (JUL-1998) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA1000 / CB15N;
RX   PubMed=20472802; DOI=10.1128/jb.00255-10;
RA   Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA   Walunas T.L., Crosson S.;
RT   "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL   J. Bacteriol. 192:3678-3688(2010).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF076983; AAC36331.1; -; Genomic_DNA.
DR   EMBL; CP001340; ACL95501.1; -; Genomic_DNA.
DR   RefSeq; WP_010919825.1; NC_011916.1.
DR   RefSeq; YP_002517409.1; NC_011916.1.
DR   AlphaFoldDB; B8GX11; -.
DR   SMR; B8GX11; -.
DR   PRIDE; B8GX11; -.
DR   EnsemblBacteria; ACL95501; ACL95501; CCNA_02036.
DR   GeneID; 7333367; -.
DR   KEGG; ccs:CCNA_02036; -.
DR   PATRIC; fig|565050.3.peg.1994; -.
DR   HOGENOM; CLU_105066_3_3_5; -.
DR   OMA; TTVAKFK; -.
DR   OrthoDB; 1847472at2; -.
DR   PhylomeDB; B8GX11; -.
DR   Proteomes; UP000001364; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..92
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000378293"
FT   REGION          58..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        76
FT                   /note="K -> N (in Ref. 1; AAC36331)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   92 AA;  9667 MW;  8A8643CCFD2B05E7 CRC64;
     MTTKAELVTA IAEKAGINKN QAKDALEAFI EAVTDSLKSG QDVRLVGFGT FKAVTRAAGT
     ARNPRTGETV NRPASKTARF QVGEGLKSSL NS