ID   DBH_DEIRA               Reviewed;         122 AA.
AC   Q9RZ89;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; OrderedLocusNames=DR_A0065;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF12250.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE001825; AAF12250.1; ALT_INIT; Genomic_DNA.
DR   PIR; C75600; C75600.
DR   RefSeq; NP_285388.1; NC_001264.1.
DR   AlphaFoldDB; Q9RZ89; -.
DR   SMR; Q9RZ89; -.
DR   STRING; 243230.DR_A0065; -.
DR   EnsemblBacteria; AAF12250; AAF12250; DR_A0065.
DR   KEGG; dra:DR_A0065; -.
DR   PATRIC; fig|243230.17.peg.2949; -.
DR   eggNOG; COG0776; Bacteria.
DR   HOGENOM; CLU_105066_3_0_0; -.
DR   InParanoid; Q9RZ89; -.
DR   OMA; PAHEGIN; -.
DR   OrthoDB; 1847472at2; -.
DR   Proteomes; UP000002524; Chromosome II.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..122
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104934"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   122 AA;  12289 MW;  C888AC1A5D3866F3 CRC64;
     MTKKSTKAPA KKAAPAAKAA PAAKRGAAAD SGKVAKTQLV EMVADQTGLT KKQSEEAISS
     MLECVVSALQ SGKSVGLPGL GTLSVKETAA RTGVRPGTSE KIQIPAGKKV AFKVASTLKG
     NL