ID   DBH_GUITH               Reviewed;          93 AA.
AC   P29214;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=DNA-binding protein HU homolog;
DE   AltName: Full=Histone-like protein;
GN   Name=hup; Synonyms=hcfC, hlp, hlpA;
OS   Guillardia theta (Cryptophyte) (Cryptomonas phi).
OG   Plastid; Chloroplast.
OC   Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX   NCBI_TaxID=55529;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1961745; DOI=10.1073/pnas.88.23.10783;
RA   Wang S., Liu X.-Q.;
RT   "The plastid genome of Cryptomonas phi encodes an hsp70-like protein, a
RT   histone-like protein, and an acyl carrier protein.";
RL   Proc. Natl. Acad. Sci. U.S.A. 88:10783-10787(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9929392; DOI=10.1007/pl00006462;
RA   Douglas S.E., Penny S.L.;
RT   "The plastid genome of the cryptophyte alga, Guillardia theta: complete
RT   sequence and conserved synteny groups confirm its common ancestry with red
RT   algae.";
RL   J. Mol. Evol. 48:236-244(1999).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF041468; AAC35701.1; -; Genomic_DNA.
DR   RefSeq; NP_050767.1; NC_000926.1.
DR   AlphaFoldDB; P29214; -.
DR   SMR; P29214; -.
DR   GeneID; 857075; -.
DR   HOGENOM; CLU_105066_3_1_1; -.
DR   OMA; PAHEGIN; -.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   Chloroplast; DNA condensation; DNA-binding; Plastid.
FT   CHAIN           1..93
FT                   /note="DNA-binding protein HU homolog"
FT                   /id="PRO_0000104998"
SQ   SEQUENCE   93 AA;  10582 MW;  2B2AA3D6D50B5E40 CRC64;
     MNKSQLISKI AYYTKYSKTD IEKIITSMLE IIVDTVATGE KVTLVGFGSF EARERKAREG
     RNPRTGEKLF LPASRIPTFS VGNFFRNKVN KTF