ID   DBH_HELPJ               Reviewed;          94 AA.
AC   Q9ZL08;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; OrderedLocusNames=jhp_0774;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AE001439; AAD06354.1; -; Genomic_DNA.
DR   PIR; H71888; H71888.
DR   RefSeq; WP_001029103.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZL08; -.
DR   SMR; Q9ZL08; -.
DR   STRING; 85963.jhp_0774; -.
DR   EnsemblBacteria; AAD06354; AAD06354; jhp_0774.
DR   KEGG; hpj:jhp_0774; -.
DR   PATRIC; fig|85963.30.peg.201; -.
DR   eggNOG; COG0776; Bacteria.
DR   OMA; IAEANPH; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding.
FT   CHAIN           1..94
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104945"
SQ   SEQUENCE   94 AA;  10408 MW;  7D2F73DE3DE1032D CRC64;
     MNKAEFIDLV KKAGKYNSKR EAEEAINAFT LAVETALSKG ESVELVGFGK FETAEQKGKE
     GKVPGSDKTY KTEDKRVPKF KPGKILKQKV EEGK