ID   DBH_RICPR               Reviewed;          99 AA.
AC   Q9ZDZ2;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; Synonyms=hupA; OrderedLocusNames=RP171;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions. {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA14638.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ235270; CAA14638.1; ALT_INIT; Genomic_DNA.
DR   PIR; G71727; G71727.
DR   RefSeq; NP_220561.1; NC_000963.1.
DR   RefSeq; WP_004598620.1; NC_000963.1.
DR   AlphaFoldDB; Q9ZDZ2; -.
DR   SMR; Q9ZDZ2; -.
DR   STRING; 272947.RP171; -.
DR   EnsemblBacteria; CAA14638; CAA14638; CAA14638.
DR   GeneID; 57569299; -.
DR   KEGG; rpr:RP171; -.
DR   PATRIC; fig|272947.5.peg.176; -.
DR   eggNOG; COG0776; Bacteria.
DR   HOGENOM; CLU_105066_3_2_5; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding; Reference proteome.
FT   CHAIN           1..99
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104964"
FT   REGION          63..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  11156 MW;  E0F4EFB51CDB1FDD CRC64;
     MNKTEFIAFM TEHGHNNKHA AHKTLTKADA EKALNLVIES VISAIKSKHN VNLTGFGSFE
     IHHRKEREGR NPKTGAKMKI DAYNQPTFRA GRKLKEACN