ID   DBH_STRTR               Reviewed;          91 AA.
AC   P96045;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=DNA-binding protein HU;
GN   Name=hup; Synonyms=hstH;
OS   Streptococcus thermophilus.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ST11;
RX   PubMed=10545259; DOI=10.1006/plas.1999.1423;
RA   Dixon-Fyle S.M., Caro L.;
RT   "Characterization in vitro and in vivo of a new HU family protein from
RT   Streptococcus thermophilus ST11.";
RL   Plasmid 42:159-173(1999).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions.
CC   -!- SUBUNIT: Homodimer.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; Y11213; CAA72098.1; -; Genomic_DNA.
DR   RefSeq; WP_002950996.1; NZ_WMLD01000003.1.
DR   AlphaFoldDB; P96045; -.
DR   SMR; P96045; -.
DR   STRING; 322159.STER_1175; -.
DR   GeneID; 61565105; -.
DR   GeneID; 66899001; -.
DR   eggNOG; COG0776; Bacteria.
DR   OMA; PAHEGIN; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.520.10; -; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA condensation; DNA-binding.
FT   CHAIN           1..91
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104986"
SQ   SEQUENCE   91 AA;  9605 MW;  06ACF19F6836E821 CRC64;
     MANKQDLIAK VAEATELTKK DSAAAVDAVF ASIEEFLAAG EKVQLIGFGN FEVRERAARQ
     GRNPQTGETI SIAASKVPAF KAGKALKDAV K