ID   DBH_SYNY1               Reviewed;          32 AA.
AC   P02343;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=DNA-binding protein HU;
DE   Flags: Fragments;
GN   Name=hup;
OS   Synechocystis sp. (strain PCC 6701).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Chroococcaceae; Geminocystis; unclassified Geminocystis.
OX   NCBI_TaxID=1144;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=ATCC 27170;
RX   PubMed=229851; DOI=10.1016/0006-291x(79)91544-4;
RA   Aitken A., Rouviere-Yaniv J.;
RT   "Amino and carboxy terminal sequences of the DNA-binding protein HU from
RT   the Cyanobacterium Synechocystis PCC 6701 (ATCC 27170).";
RL   Biochem. Biophys. Res. Commun. 91:461-467(1979).
CC   -!- FUNCTION: Histone-like DNA-binding protein which is capable of wrapping
CC       DNA to stabilize it, and thus to prevent its denaturation under extreme
CC       environmental conditions.
CC   -!- MISCELLANEOUS: The heterogeneity suggests that there are probably two
CC       distinct DNA-binding proteins, as in E.coli.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P02343; -.
DR   SMR; P02343; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; DNA condensation; DNA-binding.
FT   CHAIN           1..32
FT                   /note="DNA-binding protein HU"
FT                   /id="PRO_0000104987"
FT   VARIANT         15
FT                   /note="T -> D"
FT   VARIANT         24
FT                   /note="F -> V"
FT   NON_CONS        27..28
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   32 AA;  3376 MW;  423F195010674F66 CRC64;
     MNKGELVDAV MAKATVTKKQ ADAFILALDI VA