DBIL5_BOVIN
ID DBIL5_BOVIN Reviewed; 87 AA.
AC Q9MZG3; Q3SYR4;
DT 24-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Diazepam-binding inhibitor-like 5;
DE AltName: Full=Endozepine-like peptide;
DE Short=ELP;
GN Name=DBIL5;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=11024294; DOI=10.1016/s0378-1119(00)00317-6;
RA Ivell R., Pusch W., Balvers M., Valentin M., Walther N., Weinbauer G.;
RT "Progressive inactivation of the haploid expressed gene for the sperm-
RT specific endozepine-like peptide (ELP) through primate evolution.";
RL Gene 255:335-345(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Crossbred X Angus; TISSUE=Liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the energy metabolism of the mature sperm.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- DEVELOPMENTAL STAGE: Specifically expressed in late haploid male germ
CC cells.
CC -!- SIMILARITY: Belongs to the ACBP family. {ECO:0000305}.
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DR EMBL; AF229798; AAF79118.1; -; mRNA.
DR EMBL; BC103431; AAI03432.1; -; mRNA.
DR RefSeq; NP_847892.1; NM_178322.3.
DR AlphaFoldDB; Q9MZG3; -.
DR SMR; Q9MZG3; -.
DR STRING; 9913.ENSBTAP00000017822; -.
DR PaxDb; Q9MZG3; -.
DR PRIDE; Q9MZG3; -.
DR Ensembl; ENSBTAT00000017822; ENSBTAP00000017822; ENSBTAG00000013395.
DR GeneID; 353112; -.
DR KEGG; bta:353112; -.
DR CTD; 13168; -.
DR VEuPathDB; HostDB:ENSBTAG00000013395; -.
DR eggNOG; KOG0817; Eukaryota.
DR GeneTree; ENSGT00940000163490; -.
DR HOGENOM; CLU_118853_4_1_1; -.
DR InParanoid; Q9MZG3; -.
DR OMA; LDAMRIY; -.
DR OrthoDB; 426377at2759; -.
DR TreeFam; TF335802; -.
DR Proteomes; UP000009136; Chromosome 19.
DR Bgee; ENSBTAG00000013395; Expressed in semen and 18 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000062; F:fatty-acyl-CoA binding; IBA:GO_Central.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR Gene3D; 1.20.80.10; -; 1.
DR InterPro; IPR022408; Acyl-CoA-binding_prot_CS.
DR InterPro; IPR000582; Acyl-CoA-binding_protein.
DR InterPro; IPR035984; Acyl-CoA-binding_sf.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR Pfam; PF00887; ACBP; 1.
DR PRINTS; PR00689; ACOABINDINGP.
DR SUPFAM; SSF47027; SSF47027; 1.
DR PROSITE; PS00880; ACB_1; 1.
DR PROSITE; PS51228; ACB_2; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Lipid-binding; Reference proteome; Transport.
FT CHAIN 1..87
FT /note="Diazepam-binding inhibitor-like 5"
FT /id="PRO_0000214023"
FT DOMAIN 2..87
FT /note="ACB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00573"
FT BINDING 29..33
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
FT BINDING 55
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
FT BINDING 74
FT /ligand="an acyl-CoA"
FT /ligand_id="ChEBI:CHEBI:58342"
FT /evidence="ECO:0000250"
SQ SEQUENCE 87 AA; 9788 MW; 0CB7A1262FA1EFBE CRC64;
MCQVEFEMAC AAIKQLKGPV SDQEKLLVYS YYKQATQGDC NIPAPPATDL KAKAKWEAWN
ENKGMSKMDA MRIYIAKVEE LKKNEAG
