ID   DBPA_BORBU              Reviewed;         191 AA.
AC   O50917; O06876; Q9R8Q5;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Decorin-binding protein A;
DE   Flags: Precursor;
GN   Name=dbpA; OrderedLocusNames=BB_A24;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OG   Plasmid lp54.
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 53899 / 297;
RX   PubMed=7642279; DOI=10.1128/iai.63.9.3467-3472.1995;
RA   Guo B.P., Norris S.J., Rosenberg L.C., Hook M.;
RT   "Adherence of Borrelia burgdorferi to the proteoglycan decorin.";
RL   Infect. Immun. 63:3467-3472(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=3028, ATCC 35210 / DSM 4680 / CIP 102532 / B31, HBNC, LP7, and
RC   Sh-2-82;
RX   PubMed=9784533; DOI=10.1128/iai.66.11.5275-5285.1998;
RA   Roberts W.C., Mullikin B.A., Lathigra R., Hanson M.S.;
RT   "Molecular analysis of sequence heterogeneity among genes encoding decorin
RT   binding proteins A and B of Borrelia burgdorferi sensu lato.";
RL   Infect. Immun. 66:5275-5285(1998).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- FUNCTION: Binds to decorin which may mediate the adherence of
CC       B.burgdorferi to collagen fibers in skin and other tissues.
CC   -!- SIMILARITY: Belongs to the decorin-binding protein family.
CC       {ECO:0000305}.
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DR   EMBL; U75866; AAD05353.1; -; Genomic_DNA.
DR   EMBL; AF069253; AAC70026.1; -; Genomic_DNA.
DR   EMBL; AF069255; AAC70030.1; -; Genomic_DNA.
DR   EMBL; AF069257; AAC70034.1; -; Genomic_DNA.
DR   EMBL; AF069286; AAC70064.1; -; Genomic_DNA.
DR   EMBL; AF069269; AAC70047.1; -; Genomic_DNA.
DR   EMBL; AF069275; AAC70053.1; -; Genomic_DNA.
DR   EMBL; AE000790; AAC66250.1; -; Genomic_DNA.
DR   PIR; H70209; H70209.
DR   RefSeq; NP_045697.1; NC_001857.2.
DR   RefSeq; WP_010890380.1; NC_001857.2.
DR   PDB; 2LQU; NMR; -; A=24-191.
DR   PDBsum; 2LQU; -.
DR   AlphaFoldDB; O50917; -.
DR   BMRB; O50917; -.
DR   SMR; O50917; -.
DR   EnsemblBacteria; AAC66250; AAC66250; BB_A24.
DR   KEGG; bbu:BB_A24; -.
DR   PATRIC; fig|224326.49.peg.1541; -.
DR   HOGENOM; CLU_124841_0_0_12; -.
DR   OMA; GEFSAMY; -.
DR   Proteomes; UP000001807; Plasmid lp54.
DR   GO; GO:0016020; C:membrane; IDA:CAFA.
DR   Gene3D; 1.20.1420.40; -; 1.
DR   InterPro; IPR003332; Decorin-bd.
DR   InterPro; IPR038353; Decorin-db_sf.
DR   Pfam; PF02352; Decorin_bind; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Plasmid; Reference proteome; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..191
FT                   /note="Decorin-binding protein A"
FT                   /id="PRO_0000021074"
FT   VARIANT         34
FT                   /note="R -> K (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         37
FT                   /note="R -> S (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         41..43
FT                   /note="DIT -> AIV (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         52
FT                   /note="D -> K (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         55..56
FT                   /note="LK -> SM (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         128
FT                   /note="K -> E (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         140
FT                   /note="D -> M (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         169
FT                   /note="T -> K (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         172..173
FT                   /note="YC -> QD (in strain: 297, LP7 and Sh-2-82)"
FT   VARIANT         179..191
FT                   /note="ENSTFTDEKCKNN -> NTEDSTAKS (in strain: 297, LP7 and
FT                   Sh-2-82)"
FT   TURN            28..30
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           31..55
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   STRAND          72..74
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           76..103
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   TURN            104..106
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           108..129
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           134..144
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           150..175
FT                   /evidence="ECO:0007829|PDB:2LQU"
FT   HELIX           177..180
FT                   /evidence="ECO:0007829|PDB:2LQU"
SQ   SEQUENCE   191 AA;  21214 MW;  AD1F191C774AFEA1 CRC64;
     MIKCNNKTFN NLLKLTILVN LLISCGLTGA TKIRLERSAK DITDEIDAIK KDAALKGVNF
     DAFKDKKTGS GVSENPFILE AKVRATTVAE KFVIAIEEEA TKLKETGSSG EFSAMYDLMF
     EVSKPLQKLG IQEMTKTVSD AAEENPPTTA QGVLEIAKKM REKLQRVHTK NYCTLKKKEN
     STFTDEKCKN N