DBPB_BORBN
ID DBPB_BORBN Reviewed; 187 AA.
AC C6C2E5; O50918; O52611;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Decorin-binding protein B;
DE Flags: Precursor;
GN Name=dbpB; OrderedLocusNames=BbuN40_A25;
OS Borreliella burgdorferi (strain N40) (Borrelia burgdorferi).
OG Plasmid lp54, and Plasmid N40_lp54.
OC Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX NCBI_TaxID=521007;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=N40; PLASMID=lp54;
RX PubMed=9596756; DOI=10.1128/iai.66.6.2827-2835.1998;
RA Feng S., Hodzic E., Stevenson B., Barthold S.W.;
RT "Humoral immunity to Borrelia burgdorferi N40 decorin binding proteins
RT during infection of laboratory mice.";
RL Infect. Immun. 66:2827-2835(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=N40; PLASMID=lp54;
RX PubMed=10899883; DOI=10.1128/iai.68.8.4759-4764.2000;
RA Hagman K.E., Yang X., Wikel S.K., Schoeler G.B., Caimano M.J., Radolf J.D.,
RA Norgard M.V.;
RT "Decorin-binding protein A (DbpA) of Borrelia burgdorferi is not protective
RT when immunized mice are challenged via tick infestation and correlates with
RT the lack of DbpA expression by B. burgdorferi in ticks.";
RL Infect. Immun. 68:4759-4764(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N40; PLASMID=N40_lp54;
RX PubMed=20935092; DOI=10.1128/jb.01158-10;
RA Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J.,
RA Mongodin E.F., Luft B.J.;
RT "Whole-genome sequences of thirteen isolates of Borrelia burgdorferi.";
RL J. Bacteriol. 193:1018-1020(2011).
CC -!- FUNCTION: Binds to decorin which may mediate the adherence of
CC B.burgdorferi to collagen fibers in skin and other tissues.
CC -!- SIMILARITY: Belongs to the decorin-binding protein family.
CC {ECO:0000305}.
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DR EMBL; U69553; AAC18819.1; -; Genomic_DNA.
DR EMBL; AF005052; AAD01214.1; -; Genomic_DNA.
DR EMBL; AF042796; AAC18824.1; -; Genomic_DNA.
DR EMBL; CP001651; ACS94774.1; -; Genomic_DNA.
DR RefSeq; WP_010258353.1; NC_013130.1.
DR AlphaFoldDB; C6C2E5; -.
DR BMRB; C6C2E5; -.
DR SMR; C6C2E5; -.
DR KEGG; bbn:BbuN40_A25; -.
DR HOGENOM; CLU_124841_0_0_12; -.
DR OMA; AKCNPIS; -.
DR Gene3D; 1.20.1420.40; -; 1.
DR InterPro; IPR003332; Decorin-bd.
DR InterPro; IPR038353; Decorin-db_sf.
DR Pfam; PF02352; Decorin_bind; 1.
PE 3: Inferred from homology;
KW Plasmid; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..187
FT /note="Decorin-binding protein B"
FT /id="PRO_0000406315"
SQ SEQUENCE 187 AA; 20431 MW; E2B02C7B919C86A2 CRC64;
MKIGKLNSIV MVLFFDLLVA CSIGLVERTN AALESSSKDL KNKILKIKKE ATGKGVLFEA
FTGLKTGSKV TSGGLALREA KVQAIVETGK FLKIIEEEAL KLKETGNSGQ FLAMFDLMLE
VVESLEDVGI IGLKARVLEE SKNNPINTAE RLLAAKAQIE NQLKVVKEKQ NIENGGEKKN
NKSKKKK