ACTP_PECAS
ID ACTP_PECAS Reviewed; 552 AA.
AC Q6D913;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Cation/acetate symporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate permease {ECO:0000255|HAMAP-Rule:MF_01426};
DE AltName: Full=Acetate transporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
GN Name=actP {ECO:0000255|HAMAP-Rule:MF_01426}; OrderedLocusNames=ECA0806;
OS Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS carotovora subsp. atroseptica).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Pectobacterium.
OX NCBI_TaxID=218491;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SCRI 1043 / ATCC BAA-672;
RX PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT subsp. atroseptica and characterization of virulence factors.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC -!- FUNCTION: Transports acetate. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01426}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01426}.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000255|HAMAP-Rule:MF_01426}.
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DR EMBL; BX950851; CAG73720.1; -; Genomic_DNA.
DR RefSeq; WP_011092413.1; NC_004547.2.
DR AlphaFoldDB; Q6D913; -.
DR SMR; Q6D913; -.
DR STRING; 218491.ECA0806; -.
DR EnsemblBacteria; CAG73720; CAG73720; ECA0806.
DR GeneID; 57207534; -.
DR KEGG; eca:ECA0806; -.
DR PATRIC; fig|218491.5.peg.805; -.
DR eggNOG; COG4147; Bacteria.
DR HOGENOM; CLU_018808_8_3_6; -.
DR OMA; GTTWVQM; -.
DR OrthoDB; 278483at2; -.
DR Proteomes; UP000007966; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0015123; F:acetate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043879; F:glycolate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1730.10; -; 1.
DR HAMAP; MF_01426; Acet_symport_ActP; 1.
DR InterPro; IPR014083; Cation/Ac_symporter_ActP.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR018212; Na/solute_symporter_CS.
DR Pfam; PF00474; SSF; 1.
DR TIGRFAMs; TIGR00813; sss; 1.
DR TIGRFAMs; TIGR02711; symport_actP; 1.
DR PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR PROSITE; PS00457; NA_SOLUT_SYMP_2; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..552
FT /note="Cation/acetate symporter ActP"
FT /id="PRO_0000105410"
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 78..100
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 105..127
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 148..170
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 185..207
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 266..288
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 301..323
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 364..386
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 465..487
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT TRANSMEM 497..519
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
SQ SEQUENCE 552 AA; 59336 MW; D2AC653BEFE239F7 CRC64;
MKIRFMMLFG LLTLPVLAWA ADALTGDVQR QPLNIQAIVM FLLFVGGTLY ITYWASKKTR
SRSDYYTAGG NITGFQNGLA IAGDYMSAAS FLGISALVYT SGYDGLIYSL GFLVGWPIIL
FLIAERLRNL GRYTFADVAS YRLKQNPIRS LSACGSLVVV ALYLIAQMVG AGKLIELLFG
LNYHVAVVLV GILMVMYVMF GGMLATTWVQ IIKAVLLLFG ATFMAVMVMK SVGFSFDALF
KQAMEVHPKG AAIMSPGGLV SDPISALSLG LGLMFGTAGL PHILMRFFTV SDAKEARKSV
FYATGFMGYF YFLTFIIGFG AILLVSANPE FKDATGALIG GNNMAAIHLA DAVGGNFFLG
FISAVAFATI LAVVAGLTLA GASAVSHDLY SNVIKKGKAT ERDELKVSKI TVLVLGVVAI
SLGILFENQN IAFMVGLAFS IAASCNFPII IISMYWSKLT TRGAMIGGWA GLLTAVILMV
LGPTIWVKIL GHAAPIYPYD YPALFSMLVA FIGIWFFSIT DRSETGQQER ARFHAQFVRS
QTGVGASKGS SH
