DC4C_ACIAD
ID DC4C_ACIAD Reviewed; 134 AA.
AC P20370; Q6FBL0;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 2.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=4-carboxymuconolactone decarboxylase;
DE Short=CMD;
DE EC=4.1.1.44;
GN Name=pcaC; OrderedLocusNames=ACIAD1710;
OS Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=62977;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2298704; DOI=10.1128/jb.172.2.956-966.1990;
RA Hartnett C., Neidle E.L., Ngai K.-L., Ornston L.N.;
RT "DNA sequences of genes encoding Acinetobacter calcoaceticus
RT protocatechuate 3,4-dioxygenase: evidence indicating shuffling of genes and
RT of DNA sequences within genes during their evolutionary divergence.";
RL J. Bacteriol. 172:956-966(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33305 / BD413 / ADP1;
RX PubMed=15514110; DOI=10.1093/nar/gkh910;
RA Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L.,
RA Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N.,
RA Weissenbach J., Marliere P., Cohen G.N., Medigue C.;
RT "Unique features revealed by the genome sequence of Acinetobacter sp. ADP1,
RT a versatile and naturally transformation competent bacterium.";
RL Nucleic Acids Res. 32:5766-5779(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) =
CC (4,5-dihydro-5-oxofuran-2-yl)-acetate + CO2; Xref=Rhea:RHEA:23348,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:58425,
CC ChEBI:CHEBI:58771; EC=4.1.1.44;
CC -!- PATHWAY: Aromatic compound metabolism; beta-ketoadipate pathway; 5-oxo-
CC 4,5-dihydro-2-furylacetate from 3-carboxy-cis,cis-muconate: step 2/2.
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DR EMBL; L05770; AAC37152.1; -; Genomic_DNA.
DR EMBL; CR543861; CAG68552.1; -; Genomic_DNA.
DR PIR; B35119; B35119.
DR RefSeq; WP_004926631.1; NC_005966.1.
DR AlphaFoldDB; P20370; -.
DR SMR; P20370; -.
DR STRING; 62977.ACIAD1710; -.
DR EnsemblBacteria; CAG68552; CAG68552; ACIAD1710.
DR GeneID; 45234097; -.
DR KEGG; aci:ACIAD1710; -.
DR eggNOG; COG0599; Bacteria.
DR HOGENOM; CLU_070025_3_1_6; -.
DR OMA; EFNYGQI; -.
DR OrthoDB; 1792151at2; -.
DR BioCyc; ASP62977:ACIAD_RS07880-MON; -.
DR UniPathway; UPA00157; UER00266.
DR Proteomes; UP000000430; Chromosome.
DR GO; GO:0047575; F:4-carboxymuconolactone decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0051920; F:peroxiredoxin activity; IEA:InterPro.
DR GO; GO:0042952; P:beta-ketoadipate pathway; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.1290.10; -; 1.
DR InterPro; IPR029032; AhpD-like.
DR InterPro; IPR003779; CMD-like.
DR InterPro; IPR012788; Decarb_PcaC.
DR Pfam; PF02627; CMD; 1.
DR SUPFAM; SSF69118; SSF69118; 1.
DR TIGRFAMs; TIGR02425; decarb_PcaC; 1.
PE 4: Predicted;
KW Aromatic hydrocarbons catabolism; Decarboxylase; Lyase; Reference proteome.
FT CHAIN 1..134
FT /note="4-carboxymuconolactone decarboxylase"
FT /id="PRO_0000079798"
FT CONFLICT 79..80
FT /note="MH -> ID (in Ref. 1; AAC37152)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 134 AA; 15364 MW; DEE1D61BE1C28A60 CRC64;
MNDEQRYKQG LEVRTEVLGE KHVNRSLENL NDFNQDFQNF ISRFAWGEVW SRPGLPRHTR
SLVTIAVLLA LGREDELRMH LRACFNNGVT KDELKELILH CSLYAGLPAS NAAMHMAEEV
FKDLGIAPEK VNKD
