ID   ACTP_PECCP              Reviewed;         552 AA.
AC   C6D930;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Cation/acetate symporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
DE   AltName: Full=Acetate permease {ECO:0000255|HAMAP-Rule:MF_01426};
DE   AltName: Full=Acetate transporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
GN   Name=actP {ECO:0000255|HAMAP-Rule:MF_01426}; OrderedLocusNames=PC1_0683;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transports acetate. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01426}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01426}.
CC   -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01426}.
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DR   EMBL; CP001657; ACT11738.1; -; Genomic_DNA.
DR   RefSeq; WP_012773383.1; NC_012917.1.
DR   AlphaFoldDB; C6D930; -.
DR   SMR; C6D930; -.
DR   STRING; 561230.PC1_0683; -.
DR   EnsemblBacteria; ACT11738; ACT11738; PC1_0683.
DR   KEGG; pct:PC1_0683; -.
DR   eggNOG; COG4147; Bacteria.
DR   HOGENOM; CLU_018808_8_3_6; -.
DR   OMA; GTTWVQM; -.
DR   OrthoDB; 278483at2; -.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015123; F:acetate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043879; F:glycolate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1730.10; -; 1.
DR   HAMAP; MF_01426; Acet_symport_ActP; 1.
DR   InterPro; IPR014083; Cation/Ac_symporter_ActP.
DR   InterPro; IPR038377; Na/Glc_symporter_sf.
DR   InterPro; IPR001734; Na/solute_symporter.
DR   InterPro; IPR018212; Na/solute_symporter_CS.
DR   Pfam; PF00474; SSF; 1.
DR   TIGRFAMs; TIGR00813; sss; 1.
DR   TIGRFAMs; TIGR02711; symport_actP; 1.
DR   PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR   PROSITE; PS00457; NA_SOLUT_SYMP_2; 1.
DR   PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Sodium;
KW   Sodium transport; Symport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..552
FT                   /note="Cation/acetate symporter ActP"
FT                   /id="PRO_1000215267"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        151..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        264..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        357..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        431..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        466..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        499..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
SQ   SEQUENCE   552 AA;  59351 MW;  1839E987096EDC17 CRC64;
     MKIRFMMLFG LLTLPVLAWA ADALTGDVQR QPLNIQAIVM FLLFVGGTLY ITYWASKKTR
     SRSDYYTAGG NITGFQNGLA IAGDYMSAAS FLGISALVYT SGYDGLIYSL GFLVGWPIIL
     FLIAERLRNL GRYTFADVAS YRLQQRPIRS LSACGSLVVV ALYLIAQMVG AGKLIELLFG
     LNYHVAVILV GILMVMYVMF GGMLATTWVQ IIKAVLLLFG ATFMAVMVMK SVGFSFDALF
     KQAMAVHPKG ASIMSPGGLV SDPISALSLG LGLMFGTAGL PHILMRFFTV SDAKEARKSV
     FYATGFMGYF YFLTFIIGFG AILLVSANPE FKDATGALIG GNNMAAVHLA DAVGGDFFLG
     FISAVAFATI LAVVAGLTLA GASAVSHDLY SNVIKKGKAT ERDELKVSKI TVLVLGVVAI
     SLGILFENQN IAFMVGLAFS IAASCNFPII IISMYWSKLT TRGAMIGGWA GLLTAVILMI
     LGPTIWVKIL GHATPIYPYD YPALFSMLVA FIGIWFFSIT DRSEAGQQER ARFHAQFVRS
     QTGVGASKGS SH