ID   DCC1_DICDI              Reviewed;         376 AA.
AC   Q55BA5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Probable sister chromatid cohesion protein DCC1;
GN   ORFNames=DDB_G0271400;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Loads PCNA onto primed templates regulating velocity, spacing
CC       and restart activity of replication forks. May couple DNA replication
CC       to sister chromatid cohesion (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DCC1 family. {ECO:0000305}.
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DR   EMBL; AAFI02000006; EAL71830.1; -; Genomic_DNA.
DR   RefSeq; XP_645707.1; XM_640615.1.
DR   AlphaFoldDB; Q55BA5; -.
DR   SMR; Q55BA5; -.
DR   STRING; 44689.DDB0216809; -.
DR   PaxDb; Q55BA5; -.
DR   EnsemblProtists; EAL71830; EAL71830; DDB_G0271400.
DR   GeneID; 8617900; -.
DR   KEGG; ddi:DDB_G0271400; -.
DR   dictyBase; DDB_G0271400; dcc1.
DR   eggNOG; KOG0798; Eukaryota.
DR   HOGENOM; CLU_034504_1_1_1; -.
DR   InParanoid; Q55BA5; -.
DR   OMA; YVRTPED; -.
DR   PhylomeDB; Q55BA5; -.
DR   PRO; PR:Q55BA5; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0000785; C:chromatin; ISS:UniProtKB.
DR   GO; GO:0000775; C:chromosome, centromeric region; IBA:GO_Central.
DR   GO; GO:0031390; C:Ctf18 RFC-like complex; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; ISS:UniProtKB.
DR   InterPro; IPR019128; Dcc1.
DR   PANTHER; PTHR13395; PTHR13395; 1.
DR   Pfam; PF09724; Dcc1; 1.
PE   3: Inferred from homology;
KW   Cell cycle; DNA replication; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Probable sister chromatid cohesion protein DCC1"
FT                   /id="PRO_0000318069"
FT   REGION          213..232
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  42914 MW;  A5162356C0253E12 CRC64;
     MTPNDDDDTK VITFSSDYPD TDYRFLEANQ EILDQIKNNK KLVIKGSLTD EAVLCTDDKT
     FTIRAGHTSN SMLLVSKDTN KIKVALQYHL ELTEIQPKLN VLKDLLYSKA IDNSLDFEDD
     ENLLGFSFDE IIDRIQSSEK EIQQYLLKLN TLIYKNRYIV LSENYEFKIL ELILSEATIG
     AWKLDNIPID KCIENIRAPE FIIKHCLQLY SKQKSPTNSG GGGEEIKGGG GDDNNDENIC
     SLDFNKVCIF RAKQLLTLSN KSNMKFEDFM DNWKDTLPIE IQPNFSMLKG IAILIPSSST
     NPKEKSVKFI NESILPTIPK ARFKELFQIS TRWSIDDIEP FIKSTIPPGN SLEQFILTYS
     RPITTSTGEK MIVTRF