ID   DCC1_XENLA              Reviewed;         390 AA.
AC   Q6GMB0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Sister chromatid cohesion protein DCC1;
GN   Name=dscc1; Synonyms=dcc1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Loads pcna onto primed templates regulating velocity, spacing
CC       and restart activity of replication forks. May couple DNA replication
CC       to sister chromatid cohesion (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ctf18-RFC complex which consists of ctf18,
CC       ctf8, dscc1 and the RFC complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DCC1 family. {ECO:0000305}.
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DR   EMBL; BC074160; AAH74160.1; -; mRNA.
DR   RefSeq; NP_001086076.1; NM_001092607.1.
DR   AlphaFoldDB; Q6GMB0; -.
DR   SMR; Q6GMB0; -.
DR   IntAct; Q6GMB0; 1.
DR   DNASU; 444505; -.
DR   GeneID; 444505; -.
DR   KEGG; xla:444505; -.
DR   CTD; 444505; -.
DR   Xenbase; XB-GENE-5781778; dscc1.L.
DR   OMA; YVRTPED; -.
DR   OrthoDB; 1140219at2759; -.
DR   Proteomes; UP000186698; Chromosome 6L.
DR   Bgee; 444505; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0000785; C:chromatin; ISS:UniProtKB.
DR   GO; GO:0031390; C:Ctf18 RFC-like complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0034088; P:maintenance of mitotic sister chromatid cohesion; ISS:UniProtKB.
DR   GO; GO:0006275; P:regulation of DNA replication; ISS:UniProtKB.
DR   InterPro; IPR019128; Dcc1.
DR   PANTHER; PTHR13395; PTHR13395; 1.
DR   Pfam; PF09724; Dcc1; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; DNA replication; DNA-binding; Nucleus; Reference proteome.
FT   CHAIN           1..390
FT                   /note="Sister chromatid cohesion protein DCC1"
FT                   /id="PRO_0000318067"
SQ   SEQUENCE   390 AA;  44555 MW;  AD76F02941D23DC8 CRC64;
     MSRSQEELEA TLQIAKVNPE DLRSTVHCLS FSSEFTSGDY SLMELDDTLC KQIEAGDSLV
     IRGDKSDHAV LCSQDKTYDL KIADTSNLLL FIPGCKLPDQ LPADQQPLSV IHCEIAGFSN
     HYWELRRCRP KLKKLKKLLM ENTYNGPENE SESSQETSLY TTEDLLSVIQ SSTEELMDHL
     KAIHACNIKG IWRLLDFDYE MKLLNHITQL IDSESWSFSK VPLQVCLQEL RSLEPEEMIE
     HCLTCYGKRL MEEGGDCFAL DEDKICRATA LMLLQNAVKF NLAEFQEVWQ QSVPDGMNTR
     LDQLKGLALV DRTSRPETIF LLQTEDLPED TQERFNTLFG MREKWTEADI APYIQDLCGE
     KQTIGALLTK YARSSMQNGI KLFNSRRPLS