ID   DCD1A_DICDI             Reviewed;         441 AA.
AC   Q55BZ5;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Protein dcd1A;
DE   AltName: Full=Acid ceramidase-like protein A;
DE   Flags: Precursor;
GN   Name=dcd1A; ORFNames=DDB_G0270296;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   INDUCTION [LARGE SCALE ANALYSIS].
RX   PubMed=18590548; DOI=10.1186/1471-2180-8-109;
RA   Carilla-Latorre S., Calvo-Garrido J., Bloomfield G., Skelton J., Kay R.R.,
RA   Ivens A., Martinez J.L., Escalante R.;
RT   "Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common
RT   and specific effects from PAO1 and PA14 strains.";
RL   BMC Microbiol. 8:109-109(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- INDUCTION: Down-regulated by Pseudomonas aeruginosa, PAO1 strain and
CC       up-regulated by Pseudomonas aeruginosa, PA14 strain infection.
CC       {ECO:0000269|PubMed:18590548}.
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DR   EMBL; AAFI02000005; EAL72498.1; -; Genomic_DNA.
DR   RefSeq; XP_646686.1; XM_641594.1.
DR   AlphaFoldDB; Q55BZ5; -.
DR   SMR; Q55BZ5; -.
DR   PaxDb; Q55BZ5; -.
DR   PRIDE; Q55BZ5; -.
DR   EnsemblProtists; EAL72498; EAL72498; DDB_G0270296.
DR   GeneID; 8617661; -.
DR   KEGG; ddi:DDB_G0270296; -.
DR   dictyBase; DDB_G0270296; dcd1A.
DR   eggNOG; ENOG502RA4J; Eukaryota.
DR   HOGENOM; CLU_616695_0_0_1; -.
DR   InParanoid; Q55BZ5; -.
DR   OMA; HVQPSND; -.
DR   PhylomeDB; Q55BZ5; -.
DR   PRO; PR:Q55BZ5; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..441
FT                   /note="Protein dcd1A"
FT                   /id="PRO_0000384455"
FT   CARBOHYD        45
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        261
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        308
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        419
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   441 AA;  49203 MW;  C803FD07573A0E45 CRC64;
     MKIFNKLIFL IIQCILIISV TNAQVDCGGT DNPYPIYNEL PVLINQTTYG KLYKIGPPDN
     LINIIELYGT PYQRGLAQGQ LLKSEINDIF DNFFGYITVM VNELVTKYAD YLPKFLVDAL
     EEGGVGLALD ITADLTKKYT PKSFFEEMQG IADGSGIEYK TILRLHMFPE LIKAACSMVG
     AYNSATLNKG LLQLRALDFG FDPMNPLRLH PTVMIYHPES VSAGGDGGHE FATLSWAGFL
     GTLTGYSQHV GICEKYWFGY NGTSSREGIP FHFLLREIIQ FDESIDEALN RIINADRTCS
     VFMGLGSNQT NTFKAVEYSY EYVRVFDDQT PFPSYVPTPS AHPVIQDVVY IDKFVQPSNH
     QCLASVLQKS LGSIDVTSLI NAAAQLQTGD IHIGIYDYQQ NQMYVSVGTQ SGPYPPPSNF
     TIVPAYARQF IQIDLNSFFN Q