ID   ACTP_YERPA              Reviewed;         551 AA.
AC   Q1C0M8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Cation/acetate symporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
DE   AltName: Full=Acetate permease {ECO:0000255|HAMAP-Rule:MF_01426};
DE   AltName: Full=Acetate transporter ActP {ECO:0000255|HAMAP-Rule:MF_01426};
GN   Name=actP {ECO:0000255|HAMAP-Rule:MF_01426}; OrderedLocusNames=YPA_4033;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Transports acetate. {ECO:0000255|HAMAP-Rule:MF_01426}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01426}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01426}.
CC   -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC       family. {ECO:0000255|HAMAP-Rule:MF_01426}.
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DR   EMBL; CP000308; ABG15994.1; -; Genomic_DNA.
DR   RefSeq; WP_002209029.1; NZ_CP009906.1.
DR   AlphaFoldDB; Q1C0M8; -.
DR   SMR; Q1C0M8; -.
DR   EnsemblBacteria; ABG15994; ABG15994; YPA_4033.
DR   GeneID; 57974352; -.
DR   KEGG; ypa:YPA_4033; -.
DR   OMA; GTTWVQM; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0015123; F:acetate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0043879; F:glycolate transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1730.10; -; 1.
DR   HAMAP; MF_01426; Acet_symport_ActP; 1.
DR   InterPro; IPR014083; Cation/Ac_symporter_ActP.
DR   InterPro; IPR038377; Na/Glc_symporter_sf.
DR   InterPro; IPR001734; Na/solute_symporter.
DR   InterPro; IPR018212; Na/solute_symporter_CS.
DR   Pfam; PF00474; SSF; 1.
DR   TIGRFAMs; TIGR00813; sss; 1.
DR   TIGRFAMs; TIGR02711; symport_actP; 1.
DR   PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR   PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Sodium;
KW   Sodium transport; Symport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..551
FT                   /note="Cation/acetate symporter ActP"
FT                   /id="PRO_1000024344"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        207..227
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        356..376
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        406..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        469..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
FT   TRANSMEM        498..518
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01426"
SQ   SEQUENCE   551 AA;  59310 MW;  38FAE74375AD9BD6 CRC64;
     MKIRHWSALS LFVLPALAQA EALTGEVHRQ PLNIQAIVMF LLFVGGTLYI TYWASKRTRS
     RQDYYTAGGR ITGFQNGLAI AGDYMSAASF LGISALVYAS GYDGLIYSIG FLIGWPIILF
     LIAERLRNLG RYTFADVASY RLQQRPIRTL SACGSLVVVA LYLIAQMVGA GKLIQLLFGL
     NYHVAVVLVG ILMVLYVLFG GMLATTWVQI IKAVMLLSGA TFMAIMVMKS VNFNFNTLFS
     EAVKVHPKGL SIMSPGGLVS DPISALSLGL ALMFGTAGLP HILMRFFTVS DAKEARKSVF
     YATGFIGYFY ILTFIIGFGA ILLVGPNQTF KDAAGALLGG NNMAAVHLAN AVGGSFFLGF
     ISAVAFATIL AVVAGLTLAG ASAVSHDLYA SVIKKGKANE RDELRVSKIT VIILGIVAIG
     LGILFENQNI AFMVGLAFSI AASCNFPIII ISMYWDKLTT RGAMIGGWLG LSTAVILMIL
     GPTIWVTILG HEKPIYPYEY PALFSMIAAF VGTWFFSITD NSETGKQERL LFKSQFVRSQ
     TGLGASKGGA H