ID   DCG1_YEAST              Reviewed;         244 AA.
AC   P32460; D6VVW1;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Protein DCG1;
GN   Name=DCG1; OrderedLocusNames=YIR030C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1916277; DOI=10.1016/0378-1119(91)90464-m;
RA   Yoo H.S., Cooper T.G.;
RT   "Sequences of two adjacent genes, one (DAL2) encoding allantoicase and
RT   another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces
RT   cerevisiae.";
RL   Gene 104:55-62(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169870;
RA   Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA   Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA   Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA   Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA   Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL   Nature 387:84-87(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   INDUCTION.
RX   PubMed=16957246; DOI=10.1128/aem.00548-06;
RA   Usaite R., Patil K.R., Grotkjaer T., Nielsen J., Regenberg B.;
RT   "Global transcriptional and physiological responses of Saccharomyces
RT   cerevisiae to ammonium, L-alanine, or L-glutamine limitation.";
RL   Appl. Environ. Microbiol. 72:6194-6203(2006).
RN   [6]
RP   INDUCTION.
RX   PubMed=17308034; DOI=10.1128/mcb.01084-06;
RA   Godard P., Urrestarazu A., Vissers S., Kontos K., Bontempi G.,
RA   van Helden J., Andre B.;
RT   "Effect of 21 different nitrogen sources on global gene expression in the
RT   yeast Saccharomyces cerevisiae.";
RL   Mol. Cell. Biol. 27:3065-3086(2007).
CC   -!- INDUCTION: Expression is regulated by various nitrogen sources.
CC       {ECO:0000269|PubMed:16957246, ECO:0000269|PubMed:17308034}.
CC   -!- MISCELLANEOUS: Sensitive to nitrogen catabolite repression.
CC   -!- SIMILARITY: Belongs to the HyuE racemase family. {ECO:0000305}.
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DR   EMBL; M64719; AAA34562.1; -; Genomic_DNA.
DR   EMBL; Z38061; CAA86190.1; -; Genomic_DNA.
DR   EMBL; AY692748; AAT92767.1; -; Genomic_DNA.
DR   EMBL; BK006942; DAA08577.1; -; Genomic_DNA.
DR   PIR; S48492; S48492.
DR   RefSeq; NP_012296.1; NM_001179552.1.
DR   AlphaFoldDB; P32460; -.
DR   SMR; P32460; -.
DR   BioGRID; 35021; 9.
DR   IntAct; P32460; 1.
DR   MINT; P32460; -.
DR   STRING; 4932.YIR030C; -.
DR   iPTMnet; P32460; -.
DR   MaxQB; P32460; -.
DR   PaxDb; P32460; -.
DR   PRIDE; P32460; -.
DR   EnsemblFungi; YIR030C_mRNA; YIR030C; YIR030C.
DR   GeneID; 854848; -.
DR   KEGG; sce:YIR030C; -.
DR   SGD; S000001469; DCG1.
DR   VEuPathDB; FungiDB:YIR030C; -.
DR   eggNOG; ENOG502RZ0H; Eukaryota.
DR   HOGENOM; CLU_053002_1_0_1; -.
DR   InParanoid; P32460; -.
DR   OMA; ITSNKEW; -.
DR   BioCyc; YEAST:G3O-31447-MON; -.
DR   PRO; PR:P32460; -.
DR   Proteomes; UP000002311; Chromosome IX.
DR   RNAct; P32460; protein.
DR   GO; GO:0036361; F:racemase activity, acting on amino acids and derivatives; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEP:SGD.
DR   InterPro; IPR015942; Asp/Glu/hydantoin_racemase.
DR   Pfam; PF01177; Asp_Glu_race; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..244
FT                   /note="Protein DCG1"
FT                   /id="PRO_0000079806"
SQ   SEQUENCE   244 AA;  27313 MW;  8B5261745CC0E494 CRC64;
     METRILVVNP NSSKSMTVSL RETIEKTFSM ESCKISYFTG PDTSPPQIDG QETSIKSMEA
     CLPLLIDDQE SVYYFQKFNG ILIACFSDHP LVAKIKDRAA KEKADVSIVG LLDSSINYCN
     LVGKKFSIIT SNKEWIPILN NSVESKFLTG NTVNKNLWKG TVSTDLQVLD LHSPENFQQI
     AEIIYRENIK KLDSDIVILG CAGFSGLQNK LAKTFQRDGT LFLDTIEIGL QILITMIRFV
     NSQK