ID   ACTY_BOVIN              Reviewed;         376 AA.
AC   A4IFE3;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Beta-centractin;
DE   AltName: Full=Actin-related protein 1B;
DE            Short=ARP1B;
GN   Name=ACTR1B;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Thalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of a multi-subunit complex involved in microtubule
CC       based vesicle motility. It is associated with the centrosome (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP1 subfamily. {ECO:0000305}.
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DR   EMBL; BC134541; AAI34542.1; -; mRNA.
DR   RefSeq; NP_001096808.1; NM_001103338.1.
DR   AlphaFoldDB; A4IFE3; -.
DR   SMR; A4IFE3; -.
DR   CORUM; A4IFE3; -.
DR   PeptideAtlas; A4IFE3; -.
DR   PRIDE; A4IFE3; -.
DR   Ensembl; ENSBTAT00000081801; ENSBTAP00000059768; ENSBTAG00000048041.
DR   GeneID; 100125305; -.
DR   KEGG; bta:100125305; -.
DR   CTD; 10120; -.
DR   VEuPathDB; HostDB:ENSBTAG00000048041; -.
DR   VGNC; VGNC:54395; ACTR1B.
DR   eggNOG; KOG0676; Eukaryota.
DR   GeneTree; ENSGT00940000161587; -.
DR   InParanoid; A4IFE3; -.
DR   OMA; YTTWTGG; -.
DR   OrthoDB; 649708at2759; -.
DR   Proteomes; UP000009136; Chromosome 11.
DR   Bgee; ENSBTAG00000048041; Expressed in cardiac atrium and 106 other tissues.
DR   ExpressionAtlas; A4IFE3; baseline.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0005737; C:cytoplasm; ISS:AgBase.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; ATP-binding; Cytoplasm; Cytoskeleton; Nitration;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Beta-centractin"
FT                   /id="PRO_0000328040"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:P42025"
FT   MOD_RES         4
FT                   /note="3'-nitrotyrosine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8R5C5"
SQ   SEQUENCE   376 AA;  42294 MW;  79C55A3104DF91D4 CRC64;
     MESYDIIANQ PVVIDNGSGV IKAGFAGDQI PKYCFPNYVG RPKHMRVMAG ALEGDLFIGP
     KAEEHRGLLA IRYPMEHGVV RDWNDMERIW QYVYSKDQLQ TFSEEHPVLL TEAPLNPSKN
     REKAAEVFFE TFNVPALFIS MQAVLSLYAT GRTTGVVLDS GDGVTHAVPV YEGFAMPHSI
     MRVDIAGRDV SRYLRLLLRK EGADFHTSAE FEVVRTIKER ACYLSINPQK DEALETEKVQ
     YTLPDGSTLN VGPARFRAPE LLFQPDLIGD ESEGLHEVLV FAIHKSDMDL RRTLFANIML
     SGGSTLFKGF GDRLLSEVKK LAPKDVKIKI SAPQERLYST WIGGSILASL DTFKKMWVSK
     KEYEEDGSRA IHRKTF