DCL_ARATH
ID DCL_ARATH Reviewed; 219 AA.
AC Q9C642;
DT 10-MAY-2017, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Protein DCL homolog, chloroplastic {ECO:0000305};
DE Short=AtDCL {ECO:0000303|PubMed:15197595};
DE Flags: Precursor;
GN Name=DCL {ECO:0000303|PubMed:15197595};
GN OrderedLocusNames=At1g45230 {ECO:0000312|Araport:AT1G45230};
GN ORFNames=F2G19.1 {ECO:0000312|EMBL:AAG50632.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=15197595; DOI=10.1007/s00425-004-1295-5;
RA Bellaoui M., Gruissem W.;
RT "Altered expression of the Arabidopsis ortholog of DCL affects normal plant
RT development.";
RL Planta 219:819-826(2004).
CC -!- FUNCTION: Required for normal plastid function and plant development.
CC Required for correct plastid ribosome assembly. Required for processing
CC and maturation of 4.5S rRNA. {ECO:0000269|PubMed:15197595}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:15197595}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves, stems, flowers and siliques.
CC {ECO:0000269|PubMed:15197595}.
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DR EMBL; AC083835; AAG50632.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32113.1; -; Genomic_DNA.
DR EMBL; AY128277; AAM91086.1; -; mRNA.
DR EMBL; BT014877; AAT41860.1; -; mRNA.
DR EMBL; AK220622; BAD95026.1; -; mRNA.
DR PIR; C96510; C96510.
DR RefSeq; NP_683398.1; NM_148557.4.
DR AlphaFoldDB; Q9C642; -.
DR SMR; Q9C642; -.
DR STRING; 3702.AT1G45230.1; -.
DR iPTMnet; Q9C642; -.
DR PaxDb; Q9C642; -.
DR PRIDE; Q9C642; -.
DR ProteomicsDB; 223985; -.
DR EnsemblPlants; AT1G45230.1; AT1G45230.1; AT1G45230.
DR GeneID; 841096; -.
DR Gramene; AT1G45230.1; AT1G45230.1; AT1G45230.
DR KEGG; ath:AT1G45230; -.
DR Araport; AT1G45230; -.
DR TAIR; locus:504956149; AT1G45230.
DR eggNOG; ENOG502RXJ7; Eukaryota.
DR HOGENOM; CLU_071424_0_1_1; -.
DR OMA; YHPEVEK; -.
DR OrthoDB; 1215224at2759; -.
DR PhylomeDB; Q9C642; -.
DR PRO; PR:Q9C642; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C642; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:UniProtKB.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:UniProtKB.
DR GO; GO:1901259; P:chloroplast rRNA processing; IMP:UniProtKB.
DR InterPro; IPR044673; DCL-like.
DR PANTHER; PTHR33415; PTHR33415; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Plastid; Reference proteome; Transit peptide.
FT TRANSIT 1..48
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 49..219
FT /note="Protein DCL homolog, chloroplastic"
FT /evidence="ECO:0000255"
FT /id="PRO_0000439875"
FT REGION 70..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..96
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 25448 MW; C4061B8DA2A4C448 CRC64;
MSLASIPSSS PVASPYFRCR TYIFSFSSSP LCLYFPRGDS TSLRPRVRAL RTESDGAKIG
NSESYGSELL RRPRIASEES SEEEEEEEEE NSEGDEFVDW EDKILEVTVP LVGFVRMILH
SGKYANRDRL SPEHERTIIE MLLPYHPECE KKIGCGIDYI MVGHHPDFES SRCMFIVRKD
GEVVDFSYWK CIKGLIKKKY PLYADSFILR HFRKRRQNR
