ID   DCN1M_DICDI             Reviewed;         267 AA.
AC   Q86JM4; Q55A84;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=DCN1-like protein 2;
DE   AltName: Full=Defective in cullin neddylation protein 1-like protein 2;
GN   ORFNames=DDB_G0272016;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000007; EAL71442.1; -; Genomic_DNA.
DR   RefSeq; XP_645382.1; XM_640290.1.
DR   AlphaFoldDB; Q86JM4; -.
DR   SMR; Q86JM4; -.
DR   STRING; 44689.DDB0305271; -.
DR   EnsemblProtists; EAL71442; EAL71442; DDB_G0272016.
DR   GeneID; 8618271; -.
DR   KEGG; ddi:DDB_G0272016; -.
DR   dictyBase; DDB_G0272016; -.
DR   eggNOG; KOG3077; Eukaryota.
DR   InParanoid; Q86JM4; -.
DR   OMA; HERKCKI; -.
DR   PhylomeDB; Q86JM4; -.
DR   Reactome; R-DDI-8951664; Neddylation.
DR   PRO; PR:Q86JM4; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0097602; F:cullin family protein binding; IBA:GO_Central.
DR   GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR   GO; GO:0032182; F:ubiquitin-like protein binding; IBA:GO_Central.
DR   GO; GO:0051443; P:positive regulation of ubiquitin-protein transferase activity; IBA:GO_Central.
DR   GO; GO:0045116; P:protein neddylation; IBA:GO_Central.
DR   Gene3D; 1.10.238.200; -; 1.
DR   InterPro; IPR014764; DCN-prot.
DR   InterPro; IPR042460; DCN1-like_PONY.
DR   InterPro; IPR005176; PONY_dom.
DR   PANTHER; PTHR12281; PTHR12281; 1.
DR   Pfam; PF03556; Cullin_binding; 1.
DR   PROSITE; PS51229; DCUN1; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..267
FT                   /note="DCN1-like protein 2"
FT                   /id="PRO_0000330841"
FT   DOMAIN          75..262
FT                   /note="DCUN1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00574"
FT   REGION          1..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..34
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   267 AA;  30102 MW;  84F0906F1B140D73 CRC64;
     MTRKYTKKSS GSTASTTNST AEIVDLTTST SSVGKKRKSP DEKAQPITKK ALNSLTPVQS
     MFEKYKGKNI IKAIHYTYLY TYIFNVHLDD DETIGPEGIA RFCSDIGLAP DSFEILVLAW
     TMNASKMGYF SKNEFSSGFE KLQCSDLSTL KKQLNSTSQK LKHDSTKFTD LYKYAFGFAS
     EVESKKSVDL GTAAEMLKLL LPEGPHTTNF AAFLCTQPNK SINKDQWLCF LEFSRTVKAD
     LSNYDDSEAW PLLLDQFSEW VQQEKRI