ID   DCN1_MAGO7              Reviewed;         281 AA.
AC   Q52DM9; A4R7Z5; G4N605;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Defective in cullin neddylation protein 1;
GN   Name=DCN1; ORFNames=MGG_06627;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: May contribute to neddylation of cullin components of SCF-
CC       type E3 ubiquitin ligase complexes. Neddylation of cullins play an
CC       essential role in the regulation of SCF-type complexes activity (By
CC       similarity). {ECO:0000250}.
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DR   EMBL; CM001234; EHA50581.1; -; Genomic_DNA.
DR   RefSeq; XP_003716900.1; XM_003716852.1.
DR   AlphaFoldDB; Q52DM9; -.
DR   SMR; Q52DM9; -.
DR   STRING; 318829.MGG_06627T0; -.
DR   EnsemblFungi; MGG_06627T0; MGG_06627T0; MGG_06627.
DR   GeneID; 2684782; -.
DR   KEGG; mgr:MGG_06627; -.
DR   VEuPathDB; FungiDB:MGG_06627; -.
DR   eggNOG; KOG3077; Eukaryota.
DR   HOGENOM; CLU_047042_1_0_1; -.
DR   InParanoid; Q52DM9; -.
DR   OMA; FTQTGEQ; -.
DR   OrthoDB; 1418097at2759; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   Gene3D; 1.10.238.200; -; 1.
DR   InterPro; IPR014764; DCN-prot.
DR   InterPro; IPR042460; DCN1-like_PONY.
DR   InterPro; IPR005176; PONY_dom.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR12281; PTHR12281; 1.
DR   Pfam; PF03556; Cullin_binding; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   PROSITE; PS51229; DCUN1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..281
FT                   /note="Defective in cullin neddylation protein 1"
FT                   /id="PRO_0000129514"
FT   DOMAIN          7..44
FT                   /note="UBA-like"
FT   DOMAIN          55..267
FT                   /note="DCUN1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00574"
SQ   SEQUENCE   281 AA;  31208 MW;  74D7DDCF9823107A CRC64;
     MPLTAVQKTL SAQFVHMTAT NDKVAQKFLK NANWKLDIAA DAYFNSNPNM ATSSSSKPKL
     DKMFSDLQDT QEDSPDELGA GSAIEYASSL GVDPESVGIF VLMELVKAPA FGVITRSGFV
     EGWQATNAPA SKSGQKDYIQ SVIRNLPQDH ELFKRVYRHA FIAGRETPEQ RALPLENALV
     YWQCFFGPEM PHSKPWVAKS SQSGGTTDFL DLWTEYLKNN WSRTVSKDMW NQTLDFAVKS
     TADSTLSFWT PEGSWPSVID GFVEWLRNKG IGVASGMEVD S