ID   ACTZ_PNECA              Reviewed;         385 AA.
AC   P42023;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=Actin-2;
DE   AltName: Full=Actin II;
DE   AltName: Full=Centractin-like protein;
OS   Pneumocystis carinii.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Pneumocystidomycetes; Pneumocystidaceae; Pneumocystis.
OX   NCBI_TaxID=4754;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Fletcher L.D., Tidwell R.R., Dykstra C.C.;
RT   "Cloning and characterization of an actin II gene from Pneumocystis carinii
RT   which encodes a centractin-like protein.";
RL   Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin family. ARP1 subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L21184; AAA33782.1; -; mRNA.
DR   AlphaFoldDB; P42023; -.
DR   SMR; P42023; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..385
FT                   /note="Actin-2"
FT                   /id="PRO_0000089065"
SQ   SEQUENCE   385 AA;  43211 MW;  D3FD568DCC6F5655 CRC64;
     MEFNDVLTNQ PICIDNGSGV IKAGFAGEDQ PKSFFPSYVG RPKHLKIMAG AIEGDIFIGN
     KAQELRGLLK IKYPIEHGIV VDWDDMERIW QFIYTEELKT VSEEHPVLLT EAPLNPRTNR
     DQAAQVFFET FNVPALFTSI QAVLSLYASG RTTGVVLDSG DGVTHAVPIY EGFAMPSAIR
     RIDIAGRDVT EYLQLLLRKS GTIFHTSAEK EIVRIIKEKC SYVTLDPRKE EKEWINASIS
     GGKDYTKEEE FKLPDGNVLR LGAERFRAPE ILFDPEIIGS EYSGIHQVVV DAISRVDLDL
     RKSLFGNIVL SGGSTLTRGF GDRLLSEIRR LAVKDVKIKI FAPPERKYST WIGGSILASL
     STFRKMWVSA EEYQEDPDII HRKSI