ID   ACT_ACEPE               Reviewed;         353 AA.
AC   P53491;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Actin;
DE   Flags: Fragment;
OS   Acetabularia peniculus (Green alga) (Polyphysa peniculus).
OC   Eukaryota; Viridiplantae; Chlorophyta; Ulvophyceae; TCBD clade;
OC   Dasycladales; Polyphysaceae; Acetabularia.
OX   NCBI_TaxID=35862;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Frank S., Vugrek O., Menzel D.;
RL   Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- FUNCTION: Essential component of cell cytoskeleton; plays an important
CC       role in cytoplasmic streaming, cell shape determination, cell division,
CC       organelle movement and extension growth.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; Z28698; CAA82272.1; -; Genomic_DNA.
DR   AlphaFoldDB; P53491; -.
DR   SMR; P53491; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           <1..353
FT                   /note="Actin"
FT                   /id="PRO_0000088885"
FT   NON_TER         1
SQ   SEQUENCE   353 AA;  39510 MW;  EB22E8D1B82F6CC1 CRC64;
     AGFAGDDAPR AVFPSIVGKP KHQGVMVGMG QKDTYVGEEA QSRRGILTIR YPIEHGIVTN
     WDDMEKIWHH TFYNELRVAP EEHPVLLTEA PMNPKSNREK LTQIMFETFN VPAMYVSIQA
     VLSLYASGRT TGIVLDSGDG VSHTVPIYEG YALPHAILRL DLAGRDLTDY LTKLLMERGY
     SFTTTAEREI VRDIKKKLCY VALDIEQELT LLPRLEKSYE LPDGQVITVG SERFRCPEAL
     FNPGLLGMGS GIARYLFNSI MKCDVDIRKD LYSNTVLSGG TMMFPGIGER MQKEITTLAP
     SSMKIKVVAS PERKFSVWIG GSILSSLSTF QQMWISKEEY DEAGPAIVHR KCF