ID   ACT_ACHBI               Reviewed;         376 AA.
AC   P26182;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Actin;
OS   Achlya bisexualis (Water mold).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Achlya.
OX   NCBI_TaxID=4766;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=T5;
RX   PubMed=1779434; DOI=10.1007/bf02102805;
RA   Bhattacharya D., Stickel S.K., Sogin M.L.;
RT   "Molecular phylogenetic analysis of actin genic regions from Achlya
RT   bisexualis (Oomycota) and Costaria costata (Chromophyta).";
RL   J. Mol. Evol. 33:525-536(1991).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X59936; CAA42559.1; -; Genomic_DNA.
DR   PIR; S24408; S24408.
DR   AlphaFoldDB; P26182; -.
DR   SMR; P26182; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000088886"
SQ   SEQUENCE   376 AA;  41851 MW;  5C57690CEF76938C CRC64;
     MADDDVQALV VDNGSGMCKA GFAGDDAPRA VFPSIVGRPK HPGIMVGMDQ KDAYVGDEAQ
     SKRGVLTLKY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP LNPKANRERM
     TQIMFETFNV PAMYVNIQAV LSLYASGRTT GCVLDSGDGV SHTVPIYEGY ALPHAIVRLD
     LAGRDLTDYM MKILTERGYS FTTTAEREIV RDIKEKLTYI ALDFDQEMKT AAESSGLEKS
     YELPDGNVLV IGNERFRTPE VLFQPALIGK EASGIHDCTF QTIMKCDVDI RKDLYCNIVL
     SGGTTMYPGI SERMTKELTA LAPSTMKIKV VAPPERKYSV WIGGSILSSL STFQQMWISK
     AEYDESGPSI VHRKCF