ID   ACT_ASHGO               Reviewed;         376 AA.
AC   Q75D00; O94209; Q6JEJ0;
DT   31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Actin;
GN   Name=ACT1; OrderedLocusNames=ABR222W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
RN   [3]
RP   NUCLEOTIDE SEQUENCE OF 83-245.
RC   STRAIN=ATCC 8717 / IMI 31268;
RA   Diezmann S., Cox C.J., Schoenian G., Vilgalys R.J., Mitchell T.G.;
RT   "Molecular phylogeny and evolution of Candida and related species within
RT   the order saccharomycetales as inferred from multilocus sequence
RT   analysis.";
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 96-376.
RX   PubMed=10037140; DOI=10.1016/s0014-5793(99)00017-4;
RA   Maeting I., Schmidt G., Sahm H., Revuelta J.L., Stierhof Y.D.,
RA   Stahmann K.-P.;
RT   "Isocitrate lyase of Ashbya gossypii -- transcriptional regulation and
RT   peroxisomal localization.";
RL   FEBS Lett. 444:15-21(1999).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AE016815; AAS50995.1; -; Genomic_DNA.
DR   EMBL; AY497588; AAT12516.1; -; Genomic_DNA.
DR   EMBL; AJ131713; CAB38636.1; -; mRNA.
DR   RefSeq; NP_983171.1; NM_208524.1.
DR   AlphaFoldDB; Q75D00; -.
DR   SMR; Q75D00; -.
DR   STRING; 33169.AAS50995; -.
DR   PRIDE; Q75D00; -.
DR   EnsemblFungi; AAS50995; AAS50995; AGOS_ABR222W.
DR   GeneID; 4619281; -.
DR   KEGG; ago:AGOS_ABR222W; -.
DR   eggNOG; KOG0676; Eukaryota.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   InParanoid; Q75D00; -.
DR   OMA; FHTTAER; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000088898"
SQ   SEQUENCE   376 AA;  41733 MW;  78935A059585B7E5 CRC64;
     MDSGEVAALV IDNGSGMCKA GFAGDDAPRA VFPSIVGRPR HQGIMVGMGQ KDSYVGDEAQ
     SKRGILTLRY PIEHGIVTNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP MNPKSNREKM
     TQIMFETFNV PAFYVSIQAV LSLYSSGRTT GIVLDSGDGV THVVPIYAGF SLPHAILRID
     LAGRDMTDYL MKILSERGYS FSTTAEREIV RDIKEKLCYV ALDFEQEMQT AAQSSAIEKS
     YELPDGQVIT IGNERFRAPE ALFHPSVLGL EAAGIDQTTY NSIMKCDVDV RKELYGNIVM
     SGGTTMFPGI AERMQKEITA LAPSSMKVKI IAPPERKYSV WIGGSILASL TTFQQMWISK
     QEYDESGPSI VHHKCF