ID   ACT_ASPOR               Reviewed;         375 AA.
AC   Q2U7A3;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Actin;
GN   Name=act1; ORFNames=AO090124000010;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AP007165; BAE62562.1; -; Genomic_DNA.
DR   RefSeq; XP_001823695.1; XM_001823643.2.
DR   AlphaFoldDB; Q2U7A3; -.
DR   SMR; Q2U7A3; -.
DR   STRING; 510516.Q2U7A3; -.
DR   PRIDE; Q2U7A3; -.
DR   EnsemblFungi; BAE62562; BAE62562; AO090124000010.
DR   GeneID; 5995766; -.
DR   KEGG; aor:AO090124000010; -.
DR   VEuPathDB; FungiDB:AO090124000010; -.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   OMA; PNIMVGM; -.
DR   Proteomes; UP000006564; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..375
FT                   /note="Actin"
FT                   /id="PRO_0000248400"
SQ   SEQUENCE   375 AA;  41689 MW;  12EBC5416DD1F91B CRC64;
     MDDETAAIVI DNGSGMCKAG FAGDDAPRAV FPSLIGRPRH HGIIVGMGQK DSYVGDEAQS
     KRGVLSLHYP IEHGIVNNWD DMEKIWHHTY FNELRVASEE HPVLLTEAPI NPKSNREKMT
     QIMFETFNVP AFYVSIQAVL SLYASGRTTG IVLDSGDGVT HVVPIYEGFS MPHAIARMDL
     AGRDLTEYLV RILAERGHSF TTSAEHEIVR DIKERLCYVA LDFEQELETA AKSSSIEKSY
     ELPDGQVIAI GNERFRAPEA LFQPSLLGIE QGGIHETTFN SIQKCDVDVR KDLYGNIVMS
     GGTTLYPGIA DRLHKELVNL SPSSMKIKTI APPERKYSVW IGGSILASLS TFQQMWISKQ
     EYDESGPSIV HRKCF