DCRA_DESVH
ID DCRA_DESVH Reviewed; 669 AA.
AC P35841;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2004, sequence version 2.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Chemoreceptor protein A;
GN Name=dcrA; OrderedLocusNames=DVU_3182;
OS Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS B-1760 / Hildenborough).
OC Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC Desulfovibrionaceae; Desulfovibrio.
OX NCBI_TaxID=882;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1548224; DOI=10.1128/jb.174.6.1726-1733.1992;
RA Dolla A., Fu R., Brumlik M.J., Voordouw G.;
RT "Nucleotide sequence of dcrA, a Desulfovibrio vulgaris Hildenborough
RT chemoreceptor gene, and its expression in Escherichia coli.";
RL J. Bacteriol. 174:1726-1733(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough;
RX PubMed=15077118; DOI=10.1038/nbt959;
RA Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M.,
RA Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA Nelson W.C., Sullivan S.A., Fouts D.E., Haft D.H., Selengut J.,
RA Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G.,
RA Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V.,
RA Wall J.D., Voordouw G., Fraser C.M.;
RT "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT Desulfovibrio vulgaris Hildenborough.";
RL Nat. Biotechnol. 22:554-559(2004).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}; Periplasmic side {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000305}.
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DR EMBL; M81168; AAA23379.1; -; Genomic_DNA.
DR EMBL; AE017285; AAS97652.1; -; Genomic_DNA.
DR PIR; A42275; A42275.
DR RefSeq; WP_010940440.1; NC_002937.3.
DR RefSeq; YP_012392.1; NC_002937.3.
DR AlphaFoldDB; P35841; -.
DR SMR; P35841; -.
DR STRING; 882.DVU_3182; -.
DR PaxDb; P35841; -.
DR PRIDE; P35841; -.
DR EnsemblBacteria; AAS97652; AAS97652; DVU_3182.
DR KEGG; dvu:DVU_3182; -.
DR PATRIC; fig|882.5.peg.2887; -.
DR eggNOG; COG0840; Bacteria.
DR HOGENOM; CLU_000445_107_27_7; -.
DR OMA; HINELSQ; -.
DR PhylomeDB; P35841; -.
DR Proteomes; UP000002194; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55785; SSF55785; 1.
DR TIGRFAMs; TIGR00229; sensory_box; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
PE 3: Inferred from homology;
KW Cell membrane; Chemotaxis; Membrane; Methylation; Reference proteome;
KW Transducer; Transmembrane; Transmembrane helix.
FT CHAIN 1..669
FT /note="Chemoreceptor protein A"
FT /id="PRO_0000110564"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 209..261
FT /note="HAMP"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT DOMAIN 330..382
FT /note="PAC"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00141"
FT DOMAIN 397..633
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT CONFLICT 248
FT /note="N -> K (in Ref. 1; AAA23379)"
FT /evidence="ECO:0000305"
FT CONFLICT 456..460
FT /note="LANGE -> CQWR (in Ref. 1; AAA23379)"
FT /evidence="ECO:0000305"
FT CONFLICT 536
FT /note="V -> L (in Ref. 1; AAA23379)"
FT /evidence="ECO:0000305"
FT CONFLICT 638..649
FT /note="GIQRRVREAGDA -> ASRDGCGKQAMP (in Ref. 1; AAA23379)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 669 AA; 72984 MW; BB3079D58F3FF9A5 CRC64;
MSTQRSLGTK VMLLVSGISL FVYLILAVLT SYWQRQSALT LIDSGAVRAS ELLLDAIADP
MSKGNDTGTT EKFDAIARRY ADIRAYMTDF RGNITYSTSK DVLRRDLADV VQAPALLDKF
NAALKTDSRE EQLATIDGMA FYATIRSIPN APECHHCHGR SQPILGTLVM LQDVTPAMSE
LRLHQYETVG LSVGGLLLLV GVLSLFMRRA VISRVQRIAA VSGQIEQGDY SVSFEHDGND
ELTRLNANLA SMVTTIRDQM QYNRSVLEGI IVPLAVVDAR NRIEFINQPM CTIVSTACHE
YSGKDFSAFM QQGGVEEDIT ATVLKGGNNQ QGNISYRRDD GTVFPLHYEV SPLRDDRGAV
NGAIAVIIDL TQEEEARRRI EEQRINLLRV ADEVTGVAET LVRAAEALVT RMGELERDAT
EAASETTQVA TAMEEMNVTV TEVARNASST AEMADLANGE AQSGGTEMAN TVRETRQVAQ
RTEDLAESLH ELARRADNIG RVIEVINEIA DQTNLLALNA AIEAARAGDA GRGFAVVADE
VRKLAEKTMV ATREVEQAIA AIQQGSNDAV EVMTETRQQV EVTAGKAEDT GKVLSGIVGR
AESIADMVRN IATASEQQSS TSDEINRNVT RINDLTEGIQ RRVREAGDAI RQVEGMAQRL
EALVDGFRK
