DCRB_SHIFL
ID DCRB_SHIFL Reviewed; 185 AA.
AC P0AEE2; P37620; P76699;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Inner membrane lipoprotein DcrB {ECO:0000255|HAMAP-Rule:MF_02248};
DE Flags: Precursor;
GN Name=dcrB {ECO:0000255|HAMAP-Rule:MF_02248};
GN OrderedLocusNames=SF3490, S4273;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC envelope integrity and membrane homeostasis. Essential for lipoprotein
CC maturation under conditions where membrane fluidity may be altered.
CC {ECO:0000255|HAMAP-Rule:MF_02248}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_02248};
CC Lipid-anchor {ECO:0000255|HAMAP-Rule:MF_02248}; Periplasmic side
CC {ECO:0000255|HAMAP-Rule:MF_02248}.
CC -!- SIMILARITY: Belongs to the DcrB family. {ECO:0000255|HAMAP-
CC Rule:MF_02248}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAN44949.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC Sequence=AAP19233.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE005674; AAN44949.1; ALT_INIT; Genomic_DNA.
DR EMBL; AE014073; AAP19233.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_709242.3; NC_004337.2.
DR RefSeq; WP_001245295.1; NZ_WPGW01000010.1.
DR AlphaFoldDB; P0AEE2; -.
DR SMR; P0AEE2; -.
DR STRING; 198214.SF3490; -.
DR EnsemblBacteria; AAN44949; AAN44949; SF3490.
DR EnsemblBacteria; AAP19233; AAP19233; S4273.
DR GeneID; 1026456; -.
DR GeneID; 66672644; -.
DR KEGG; sfl:SF3490; -.
DR KEGG; sfx:S4273; -.
DR PATRIC; fig|198214.7.peg.4111; -.
DR HOGENOM; CLU_125378_0_0_6; -.
DR OMA; ACDNSDT; -.
DR OrthoDB; 1288427at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR HAMAP; MF_02248; DcrB; 1.
DR InterPro; IPR046406; DcrB.
DR InterPro; IPR014894; DcrB/EagT6.
DR Pfam; PF08786; DcrB; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02248"
FT CHAIN 20..185
FT /note="Inner membrane lipoprotein DcrB"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02248"
FT /id="PRO_0000043343"
FT LIPID 20
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02248"
FT LIPID 20
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_02248"
SQ SEQUENCE 185 AA; 19787 MW; 8412B6A4028750B2 CRC64;
MRNLVKYVGI GLLVMGLAAC DDKDTNATAQ GSVAESNATG NPVNLLDGKL SFSLPADMTD
QSGKLGTQAN NMHVWSDATG QKAVIVIMGD DPKEDLAVLA KRLEDQQRSR DPQLQVVTNK
AIELKGHKMQ QLDSIISAKG QTAYSSVILG NVGNQLLTMQ ITLPADDQQK AQTTAENIIN
TLVIQ
