ID   DCT5_CAEEL              Reviewed;         207 AA.
AC   Q09304;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Protein dct-5;
DE   AltName: Full=Daf-16/foxo controlled, germline tumor affecting protein 5;
GN   Name=dct-5; ORFNames=F07F6.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   FUNCTION.
RX   PubMed=16380712; DOI=10.1038/ng1723;
RA   Oh S.W., Mukhopadhyay A., Dixit B.L., Raha T., Green M.R., Tissenbaum H.A.;
RT   "Identification of direct DAF-16 targets controlling longevity, metabolism
RT   and diapause by chromatin immunoprecipitation.";
RL   Nat. Genet. 38:251-257(2006).
RN   [3]
RP   FUNCTION.
RX   PubMed=17934462; DOI=10.1038/ng.2007.1;
RA   Pinkston-Gosse J., Kenyon C.;
RT   "DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis
RT   elegans.";
RL   Nat. Genet. 39:1403-1409(2007).
CC   -!- FUNCTION: Acts downstream of daf-16/foxo to suppress tumors induced by
CC       disruption of gld-1. Potentially a direct target of daf-15/foxo.
CC       {ECO:0000269|PubMed:16380712, ECO:0000269|PubMed:17934462}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; FO081043; CCD68753.1; -; Genomic_DNA.
DR   PIR; T15965; T15965.
DR   RefSeq; NP_495031.2; NM_062630.4.
DR   AlphaFoldDB; Q09304; -.
DR   STRING; 6239.F07F6.5; -.
DR   PaxDb; Q09304; -.
DR   PeptideAtlas; Q09304; -.
DR   EnsemblMetazoa; F07F6.5.1; F07F6.5.1; WBGene00017218.
DR   GeneID; 184148; -.
DR   KEGG; cel:CELE_F07F6.5; -.
DR   CTD; 184148; -.
DR   WormBase; F07F6.5; CE41556; WBGene00017218; dct-5.
DR   eggNOG; ENOG502SX5D; Eukaryota.
DR   GeneTree; ENSGT00970000196417; -.
DR   HOGENOM; CLU_124063_0_0_1; -.
DR   InParanoid; Q09304; -.
DR   OMA; MVCIAAK; -.
DR   OrthoDB; 1368092at2759; -.
DR   PRO; PR:Q09304; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00017218; Expressed in larva and 2 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR035161; DUF5332.
DR   PANTHER; PTHR38612; PTHR38612; 1.
DR   Pfam; PF17266; DUF5332; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..207
FT                   /note="Protein dct-5"
FT                   /id="PRO_0000065279"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  23035 MW;  4A6FE417AF363BEA CRC64;
     MKSERVNYPV KLLNFILSIM NSYLFVLIVS IGFAESSSPK SSTSCSLMTS CAVEKCLDRG
     MVGRIITESS RDEVFGNLVE KFDMVCIAAK CGNECSQCKH CHYALEQMSA LAQGEKTSGL
     CPKLETCVFN CLTEDVSKVL SCVATRCNVH CYDGDCPSCK MISRRIFSNI CKQHSMTTQP
     QIKYEGTCPN LFMELADDYV AMKKKKL