ID   DCTA1_BRADU             Reviewed;         438 AA.
AC   Q9ANR2;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=C4-dicarboxylate transport protein 1 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA1 {ECO:0000255|HAMAP-Rule:MF_01300}; Synonyms=dctA;
GN   OrderedLocusNames=bll1718;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=USDA 110spc4;
RX   PubMed=11157954; DOI=10.1128/jb.183.4.1405-1412.2001;
RA   Goettfert M., Roethlisberger S., Kuendig C., Beck C., Marty R.,
RA   Hennecke H.;
RT   "Potential symbiosis-specific genes uncovered by sequencing a 410-kb DNA
RT   region of the Bradyrhizobium japonicum chromosome.";
RL   J. Bacteriol. 183:1405-1412(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF322012; AAG60701.1; -; Genomic_DNA.
DR   EMBL; BA000040; BAC46983.1; -; Genomic_DNA.
DR   RefSeq; NP_768358.1; NC_004463.1.
DR   RefSeq; WP_011084529.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q9ANR2; -.
DR   SMR; Q9ANR2; -.
DR   STRING; 224911.27349971; -.
DR   EnsemblBacteria; BAC46983; BAC46983; BAC46983.
DR   GeneID; 64067031; -.
DR   KEGG; bja:bll1718; -.
DR   PATRIC; fig|224911.44.peg.1182; -.
DR   eggNOG; COG1301; Bacteria.
DR   HOGENOM; CLU_019375_7_0_5; -.
DR   InParanoid; Q9ANR2; -.
DR   OMA; AQIYGIP; -.
DR   PhylomeDB; Q9ANR2; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015138; F:fumarate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015366; F:malate:proton symporter activity; IBA:GO_Central.
DR   GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0070778; P:L-aspartate transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..438
FT                   /note="C4-dicarboxylate transport protein 1"
FT                   /id="PRO_0000202091"
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        160..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        192..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        229..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        324..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        361..383
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   438 AA;  46179 MW;  354B361D5C28707F CRC64;
     MTTMATAAPV RASQAWYKIL YVQVLIAILI GAMVGCLWPS VATNDWVKAL GDGFIKLIKM
     VIAPIIFCTV TSGIAHIQDA KKVGCVGVKA LFYFEIVSSF ALLLGLAMGN LVRIGHGLAV
     KPDAAAVANY VKQAEASKTV DFILNIIPDS VVGAFARGDV LQVLLFAILF GFSLMALGKR
     GERLRGMIDD VAHAVFGVIA IVMKAAPIGA FGAMAFTVGK FGPAALGNLI GLIALFYVTA
     ALFVVVVLGL IARLVGFSIF KFLIYIKDEL LIVLGTSSSE SALPQLMEKL ERLGCSKPVV
     GLVVPTGYSF NLDGTNIYMT LATLFIAQAL GVDLSFGQQL TILLVAMLTS KGASGVTGAG
     FITLAATLSV VNPALVPGMA IVFSIDKFMS EVRALTNIIG NGIAAVFVSW WESELDHVTL
     QTRLNKSTAS TTIDTTST