ID   DCTA1_BRASO             Reviewed;         439 AA.
AC   A4YQF7;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=C4-dicarboxylate transport protein 1 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA1 {ECO:0000255|HAMAP-Rule:MF_01300}; OrderedLocusNames=BRADO2301;
OS   Bradyrhizobium sp. (strain ORS 278).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium; unclassified Bradyrhizobium.
OX   NCBI_TaxID=114615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ORS 278;
RX   PubMed=17540897; DOI=10.1126/science.1139548;
RA   Giraud E., Moulin L., Vallenet D., Barbe V., Cytryn E., Avarre J.-C.,
RA   Jaubert M., Simon D., Cartieaux F., Prin Y., Bena G., Hannibal L.,
RA   Fardoux J., Kojadinovic M., Vuillet L., Lajus A., Cruveiller S., Rouy Z.,
RA   Mangenot S., Segurens B., Dossat C., Franck W.L., Chang W.-S., Saunders E.,
RA   Bruce D., Richardson P., Normand P., Dreyfus B., Pignol D., Stacey G.,
RA   Emerich D., Vermeglio A., Medigue C., Sadowsky M.;
RT   "Legumes symbioses: absence of nod genes in photosynthetic bradyrhizobia.";
RL   Science 316:1307-1312(2007).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-Rule:MF_01300}.
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DR   EMBL; CU234118; CAL76133.1; -; Genomic_DNA.
DR   RefSeq; WP_011925352.1; NC_009445.1.
DR   AlphaFoldDB; A4YQF7; -.
DR   SMR; A4YQF7; -.
DR   STRING; 114615.BRADO2301; -.
DR   EnsemblBacteria; CAL76133; CAL76133; BRADO2301.
DR   KEGG; bra:BRADO2301; -.
DR   eggNOG; COG1301; Bacteria.
DR   HOGENOM; CLU_019375_7_0_5; -.
DR   OMA; QATNTPM; -.
DR   OrthoDB; 781228at2; -.
DR   BioCyc; BSP114615:BRADO_RS10775-MON; -.
DR   Proteomes; UP000001994; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..439
FT                   /note="C4-dicarboxylate transport protein 1"
FT                   /id="PRO_0000321973"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   439 AA;  46397 MW;  7380550E76E1437E CRC64;
     MSATTPAAAA PKKPFYRVLY IQVLVAIVLG VIVGWLWPEI GKNDWIKALG DGFVKLIKMV
     IAPVIFCTVV SGIAHVSEVK KVGRVAIKAL IYFEIVSTFA LALGLIVANV IQPGAGFQGQ
     TNAAAVANYA KQASEMKSVD FVLHIIPDTV VGAFAQGEIL QVLLFSILFG IALMSLGERG
     HTMRAFVDDA AHAIFGVIAI VVKAAPIGAF GAMAFTIGRY GPQALGNLAG LIATFYLTAL
     AFVIIVLGII ARIAGFSIFK FLTYIKDELL IVLGTSSSES ALPQMMEKLE RLGCSKPVVG
     LVVPTGYSFN LDGTNIYMTL ATLFIAQAMN VHLSFGEQIT ILLVAMLTSK GASGITGAGF
     ITLAGTLAAV RPELVPGMAI VLGIDKFMSE CRALTNLCGN GVACVIVAWW EGELDRDKLR
     AALDRDIDPS DVEVAVTTG