ID   DCTA1_RHILO             Reviewed;         477 AA.
AC   Q98AV2;
DT   05-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   05-MAR-2002, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=C4-dicarboxylate transport protein 1;
GN   Name=dctA1; OrderedLocusNames=mll5840;
OS   Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
OS   (Mesorhizobium loti (strain MAFF 303099)).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Mesorhizobium.
OX   NCBI_TaxID=266835;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 29417 / CECT 9101 / MAFF 303099;
RX   PubMed=11214968; DOI=10.1093/dnares/7.6.331;
RA   Kaneko T., Nakamura Y., Sato S., Asamizu E., Kato T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Ishikawa A., Kawashima K., Kimura T., Kishida Y.,
RA   Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Mochizuki Y.,
RA   Nakayama S., Nakazaki N., Shimpo S., Sugimoto M., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of the nitrogen-fixing symbiotic bacterium
RT   Mesorhizobium loti.";
RL   DNA Res. 7:331-338(2000).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       This transport system plays an important role in the energy supply of
CC       rhizobium-legume symbionts (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB52220.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000012; BAB52220.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_010913554.1; NC_002678.2.
DR   AlphaFoldDB; Q98AV2; -.
DR   SMR; Q98AV2; -.
DR   STRING; 266835.14025620; -.
DR   EnsemblBacteria; BAB52220; BAB52220; BAB52220.
DR   KEGG; mlo:mll5840; -.
DR   PATRIC; fig|266835.9.peg.4645; -.
DR   eggNOG; COG1301; Bacteria.
DR   HOGENOM; CLU_019375_7_0_5; -.
DR   OrthoDB; 781228at2; -.
DR   Proteomes; UP000000552; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..477
FT                   /note="C4-dicarboxylate transport protein 1"
FT                   /id="PRO_0000202107"
FT   TRANSMEM        21..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        342..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        368..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          435..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        435..468
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  49646 MW;  8918F4086DC09D75 CRC64;
     MLTPLAPSVK RAPRKTLFAK PYVQVLVAIL LGVAVGHFYP QIGENLKPLG DAFIKLVKMI
     IAPVIFLTVS TGIAGMSDLQ KVGRVAGKAM VYFVTFSTLA LIVGLIVGNV IQPGAGLNID
     LTSLDVQAVN GYASKAHEQS VTGFLMNMIP TTIVGAFVEG DILQVLFFSV LFGIALAMVG
     ESGKSVLSFL QDLTAPVFKL VGILMKAAPI GAFGAMAFTI GKYGIGSVAN LAMLVGTFYL
     TAFLFVFGVL GAVCRYNGFS IFSLIRYIKE ELLLVLGTSS SEAALPSLME KMEKAGAKRS
     VVGLVIPTGY SFNLDGTNIY MTLAALFIAQ ATNTDLSVGD QVLLLLVAML SSKGAAGVTG
     AGFVTLAATL SVVPAVPVAG MALILGVDRF MSECRALTNL VGNAVASLVV ARWEGELDQA
     QLKAAFCGHQ PAETSAGQPL ITPAPSNSAA SLPVESPGWS QTPDDRAAGS KQTLAGR