ID   ACT_CANAX               Reviewed;         376 AA.
AC   P14235;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Actin;
GN   Name=ACT1;
OS   Candida albicans (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=5476;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 10123;
RX   PubMed=2685762; DOI=10.1093/nar/17.22.9488;
RA   Losberger C., Ernst J.P.;
RT   "Sequence of the Candida albicans gene encoding actin.";
RL   Nucleic Acids Res. 17:9488-9488(1989).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X16377; CAA34413.1; -; Genomic_DNA.
DR   PIR; S07639; S07639.
DR   AlphaFoldDB; P14235; -.
DR   SMR; P14235; -.
DR   PRIDE; P14235; -.
DR   VEuPathDB; FungiDB:C1_13700W_A; -.
DR   VEuPathDB; FungiDB:CAWG_00082; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000088903"
SQ   SEQUENCE   376 AA;  41753 MW;  45D6937E843A3D98 CRC64;
     MDGEEVAALI IDNGSGMCKA GFAGDDAPRA VFPSLVGRPR HQGIMVGMGQ KDSYVGDEAQ
     SKRGILTLRY PIEHGIVSNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP MNPKSNREKM
     TQIMFETFNV PAFYVSIQAV LSLYSSGRTT GIVLDSGDGV THVVPIYAGF SLPHGILRID
     LAGRDLTNHL SKILSERGYS FTTSAEREIV RDIKERLCYV ALDFEQEMQT SSQSSAIEKS
     YELPDGQVIT IGNERFRAPE ALFRPADLGL EAAGIDQTTF NSIMKCDMDV RKELYGNIVM
     SGGTTMFPGI AERMQKEITA LAPSSMKVKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHHKCF