ID   DCTA2_BRADU             Reviewed;         444 AA.
AC   Q89NW0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=C4-dicarboxylate transport protein 2 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA2 {ECO:0000255|HAMAP-Rule:MF_01300}; OrderedLocusNames=blr3723;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-Rule:MF_01300}.
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DR   EMBL; BA000040; BAC48988.1; -; Genomic_DNA.
DR   RefSeq; NP_770363.1; NC_004463.1.
DR   RefSeq; WP_011086504.1; NC_004463.1.
DR   AlphaFoldDB; Q89NW0; -.
DR   SMR; Q89NW0; -.
DR   STRING; 224911.27351983; -.
DR   EnsemblBacteria; BAC48988; BAC48988; BAC48988.
DR   GeneID; 64023447; -.
DR   KEGG; bja:blr3723; -.
DR   PATRIC; fig|224911.44.peg.3386; -.
DR   eggNOG; COG1301; Bacteria.
DR   HOGENOM; CLU_019375_7_0_5; -.
DR   InParanoid; Q89NW0; -.
DR   OMA; PVNLQLC; -.
DR   PhylomeDB; Q89NW0; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015138; F:fumarate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015366; F:malate:proton symporter activity; IBA:GO_Central.
DR   GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0070778; P:L-aspartate transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..444
FT                   /note="C4-dicarboxylate transport protein 2"
FT                   /id="PRO_0000321970"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   444 AA;  46922 MW;  1149C0D06D81226F CRC64;
     MSATITATSA TATATQKKPF YRILYVQVLA AIVLGVIVGW LWPDIGKNDW IKAMGDGFVK
     LIKMAIAPII FCTVVSGIAH ISEVKKVGRV AVKALVYFEV VSTFALALGL VVANVLRPGA
     GFQGQSNAAA VAGYAKQASE MKSVDFVLHI IPDTVVGAFA QGEILQVLLF AILFGFALMG
     LGERAHTVRS FVDDVAHAMF GVISIVVKVA PIGAFGAMAY TIGRYGPQAL GNLAGLIATF
     YLTAFLFVVV GLGIIARIAG FSIFKFLKYI KDELLIVLGT SSSESALPQM MEKLEILGCS
     KSVVGLVVPT GYSFNLDGTN IYMTLATLFI AQAMNVDLSF GEQMTILVVA MLTSKGASGI
     TGAGFITLAG TLAAVRPELL PGMAIVLGID KFMSECRALT NLCGNGVACV VVAWWEGELD
     REKLRVALDR NVDPTDLEVA VTTG