ID   DCTA3_BRADU             Reviewed;         444 AA.
AC   Q89M95;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=C4-dicarboxylate transport protein 3 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA3 {ECO:0000255|HAMAP-Rule:MF_01300}; OrderedLocusNames=blr4298;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-Rule:MF_01300}.
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DR   EMBL; BA000040; BAC49563.1; -; Genomic_DNA.
DR   RefSeq; NP_770938.1; NC_004463.1.
DR   RefSeq; WP_011087071.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89M95; -.
DR   SMR; Q89M95; -.
DR   STRING; 224911.27352560; -.
DR   EnsemblBacteria; BAC49563; BAC49563; BAC49563.
DR   GeneID; 64024029; -.
DR   KEGG; bja:blr4298; -.
DR   PATRIC; fig|224911.44.peg.4039; -.
DR   eggNOG; COG1301; Bacteria.
DR   HOGENOM; CLU_019375_7_0_5; -.
DR   InParanoid; Q89M95; -.
DR   OMA; PHHKREH; -.
DR   PhylomeDB; Q89M95; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015138; F:fumarate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015366; F:malate:proton symporter activity; IBA:GO_Central.
DR   GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0070778; P:L-aspartate transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..444
FT                   /note="C4-dicarboxylate transport protein 3"
FT                   /id="PRO_0000321971"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        198..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        399..419
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   444 AA;  46696 MW;  2718F94CE56721D3 CRC64;
     MTTTTMAGTP VAPAAAKPWY KVLYVQVLIA IVLGAIVGWL WPTVATNDWI KALGDGFIKL
     IKMVIAPIIF CTVVSGIAHI QDAKKVGRIG VKALVYFEVV STFALVIGLI IGNLVRPGAG
     FGNAAANEAA VATYAKQAAG QKSVDFVLHI IPDTVVGAFA QGEILQVLLF SVLFGFAIMS
     LGERGHTIRS FIDDAAHAVF GVISIVMRAA PIGAFGAMAY TIGKFGTGAI LNLIGLIATF
     YVTAALFVFV VLGIIARLAG FSIFKFLAYI KDELLIVLGT SSSESALPSL MEKLERLGCS
     KSVVGLVVPT GYSFNLDGTN IYMTLATLFI AQALGFDLSF GQQLTILVVA MLTSKGASGI
     TGAGFITLAA TLAVVDPRLV PGMAIVLGID KFMSECRALT NLCGNGVACV IVAWWEGELD
     RDKLNAGLSR QIDPTDMETA ITTD