ID   ACT_CANDC               Reviewed;         376 AA.
AC   Q9UVZ8; B9W9Y8;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Actin;
GN   Name=ACT1; ORFNames=CD36_12690;
OS   Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS   NRRL Y-17841) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=573826;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10463153; DOI=10.1099/13500872-145-8-1871;
RA   Donnelly S.M., Sullivan D.J., Shanley D.B., Coleman D.C.;
RT   "Phylogenetic analysis and rapid identification of Candida dubliniensis
RT   based on analysis of ACT1 intron and exon sequences.";
RL   Microbiology 145:1871-1882(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841;
RX   PubMed=19745113; DOI=10.1101/gr.097501.109;
RA   Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA   Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA   de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA   Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA   Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT   "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT   Candida albicans.";
RL   Genome Res. 19:2231-2244(2009).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; AJ236897; CAB53863.1; -; Genomic_DNA.
DR   EMBL; FM992688; CAX45626.1; -; Genomic_DNA.
DR   RefSeq; XP_002417908.1; XM_002417863.1.
DR   AlphaFoldDB; Q9UVZ8; -.
DR   SMR; Q9UVZ8; -.
DR   STRING; 42374.XP_002417908.1; -.
DR   PRIDE; Q9UVZ8; -.
DR   EnsemblFungi; CAX45626; CAX45626; CD36_12690.
DR   GeneID; 8045460; -.
DR   KEGG; cdu:CD36_12690; -.
DR   CGD; CAL0000169507; ACT1.
DR   VEuPathDB; FungiDB:CD36_12690; -.
DR   eggNOG; KOG0676; Eukaryota.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   OrthoDB; 649708at2759; -.
DR   Proteomes; UP000002605; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000088904"
SQ   SEQUENCE   376 AA;  41739 MW;  2C0DFB442300948F CRC64;
     MDGEEVAALV IDNGSGMCKA GFAGDDAPRA VFPSLVGRPR HQGIMVGMGQ KDSYVGDEAQ
     SKRGILTLRY PIEHGIVSNW DDMEKIWHHT FYNELRVAPE EHPVLLTEAP MNPKSNREKM
     TQIMFETFNV PAFYVSIQAV LSLYSSGRTT GIVLDSGDGV THVVPIYAGF SLPHGILRID
     LAGRDLTNHL SKILSERGYS FTTSAEREIV RDIKERLCYV ALDFEQEMQT SSQSSAIEKS
     YELPDGQVIT IGNERFRAPE ALFRPADLGL EAAGIDQTTF NSIMKCDMDV RKELYGNIVM
     SGGTTMFPGI AERMQKEITA LAPSSMKVKI IAPPERKYSV WIGGSILASL STFQQMWISK
     QEYDESGPSI VHHKCF