ID   ACT_CHLRE               Reviewed;         377 AA.
AC   P53498;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Actin;
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=8626057; DOI=10.1016/0378-1119(95)00711-3;
RA   Sugase Y., Hirono M., Kindle K.L., Kamiya R.;
RT   "Cloning and characterization of the actin-encoding gene of Chlamydomonas
RT   reinhardtii.";
RL   Gene 168:117-121(1996).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- FUNCTION: Essential component of cell cytoskeleton; plays an important
CC       role in cytoplasmic streaming, cell shape determination, cell division,
CC       organelle movement and extension growth.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; D50839; BAA09450.1; -; mRNA.
DR   EMBL; D50838; BAA09449.1; -; Genomic_DNA.
DR   PIR; JC4612; JC4612.
DR   RefSeq; XP_001699068.1; XM_001699016.1.
DR   PDB; 7JU4; EM; 3.40 A; u=1-377.
DR   PDBsum; 7JU4; -.
DR   AlphaFoldDB; P53498; -.
DR   SMR; P53498; -.
DR   STRING; 3055.EDO98923; -.
DR   PRIDE; P53498; -.
DR   ProMEX; P53498; -.
DR   EnsemblPlants; PNW74319; PNW74319; CHLRE_13g603700v5.
DR   GeneID; 5724669; -.
DR   Gramene; PNW74319; PNW74319; CHLRE_13g603700v5.
DR   KEGG; cre:CHLRE_13g603700v5; -.
DR   eggNOG; KOG0676; Eukaryota.
DR   HOGENOM; CLU_027965_0_2_1; -.
DR   OMA; FHTTAER; -.
DR   OrthoDB; 649708at2759; -.
DR   GO; GO:0036156; C:inner dynein arm; IDA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..377
FT                   /note="Actin"
FT                   /id="PRO_0000088909"
SQ   SEQUENCE   377 AA;  41836 MW;  4DA3F665F38111F4 CRC64;
     MADEGEVSAL VCDNGSGMVK AGFAGDDAPR AVFPSIVGRP RHTGVMVGMG QKDSYVGDEA
     QSKRGILTLR YPIEHGIVTN WDDMEKIWHH TFFNELRVAP EEHPVLLTEA PLNPKANREK
     MTQIMFETFN VPAMYVAIQA VLSLYASGRT TGIVLDSGDG VTHTVPIYEG YALPHAILRL
     DLAGRDLTDY LMKILMERGY SFTTTAEREI VRDIKEKLCY VALDFEQEMA TALSSSALEK
     TYELPDGQMI TIGNERFRCP EVLFNPNMIG MEAVGIHDTT FNSIMKCDVD IRKDLYNNIV
     LSGGTTMFPG IADRMSKEIT ALAPSAMKIK VVAPPERKYS VWIGGSILAS LSTFQQMWIA
     KSEYDESGPS IVHRKCF