ID   ACT_COSCS               Reviewed;         331 AA.
AC   P30161;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 2.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Actin;
DE   Flags: Fragment;
OS   Costaria costata (Five-ribbed kelp) (Laminaria costata).
OC   Eukaryota; Sar; Stramenopiles; Ochrophyta; PX clade; Phaeophyceae;
OC   Laminariales; Costaria.
OX   NCBI_TaxID=2872;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1779434; DOI=10.1007/bf02102805;
RA   Bhattacharya D., Stickel S.K., Sogin M.L.;
RT   "Molecular phylogenetic analysis of actin genic regions from Achlya
RT   bisexualis (Oomycota) and Costaria costata (Chromophyta).";
RL   J. Mol. Evol. 33:525-536(1991).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- FUNCTION: Essential component of cell cytoskeleton; plays an important
CC       role in cytoplasmic streaming, cell shape determination, cell division,
CC       organelle movement and extension growth.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; X59937; CAA42560.1; -; Genomic_DNA.
DR   PIR; S24409; S24409.
DR   AlphaFoldDB; P30161; -.
DR   SMR; P30161; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           <1..331
FT                   /note="Actin"
FT                   /id="PRO_0000088914"
FT   NON_TER         1
SQ   SEQUENCE   331 AA;  37224 MW;  2810B5CE0A021CFE CRC64;
     VGMDQKDAYV GDEAQSKRGV LTLKYPIEHG IVTNWDDMEK IWHHTFYNEL RVAPEEHPVL
     LTEAPLNPKA NKERMTQIMF ETFNVPAMYV NIQAVLSLYA SGRTTGCVLD SGDGVSHTVP
     IYEGYALPHA INRLDLAGRD LTDNLMKVLT ERGYSFTTTA EREIVRDIKE KLTYVALDFD
     QEMKTAAESS QLEKSYELPD GNVIVIGNER FRCPEVRFQP SFIGMESSGI HDCTFKTIMK
     CDVDIRKDLY GNIVLSGGTT MFPGIGERMT KELTALAPST MKIKVVAPPE RKYSVWIGGS
     ILASLSTFQQ MWISKAEYDE SGPSIVHRKC F