ID   ACT_CRYPV               Reviewed;         376 AA.
AC   P26183;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Actin;
OS   Cryptosporidium parvum.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=5807;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1542305; DOI=10.1016/0166-6851(92)90248-i;
RA   Kim K., Gooze L., Petersen C., Gut J., Nelson R.G.;
RT   "Isolation, sequence and molecular karyotype analysis of the actin gene of
RT   Cryptosporidium parvum.";
RL   Mol. Biochem. Parasitol. 50:105-114(1992).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; M86241; AAA28295.1; -; Genomic_DNA.
DR   PIR; A45634; A45634.
DR   AlphaFoldDB; P26183; -.
DR   SMR; P26183; -.
DR   PRIDE; P26183; -.
DR   VEuPathDB; CryptoDB:cgd5_3160; -.
DR   OMA; FHTTAER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS00432; ACTINS_2; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..376
FT                   /note="Actin"
FT                   /id="PRO_0000088918"
SQ   SEQUENCE   376 AA;  42174 MW;  87FF917ACCF46D0B CRC64;
     MSEEETQALV VDNGSGMVKA GVAGDDAPRC VFPSIVGRPK MPGVMVGMDQ KDCYVGDEAQ
     SKRGILTLKY PIEHGIVTNW EDMEKIWHHT FYNELRVAPE EHPVLLTEAP MNPKVNRERM
     TQIMFETFNV PAMYVNIQAV LSLYASGRTT GIVLDSGDGV SHTVPIYEGY AIPHAIMRLD
     LAGRDLTDFL MKILHDRGYS FTTTAEREIV RDIKEKLCYI ALDYEEEMKK SQESSELEKT
     YELPDGHVIT VGSERFRCPE ALFQPGFLGK EAVGIGETTF QSIMKCDLDI RKDLYANIVL
     SGGTTMYPGI GERMTKELTS LAPSTMKIKV VAPPERKYSV WIGGSILSSL STFQQMWITK
     EEYDESGPSI VHRKCF