ID   DCTA_YERP3              Reviewed;         429 AA.
AC   A7FP30;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=C4-dicarboxylate transport protein {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA {ECO:0000255|HAMAP-Rule:MF_01300};
GN   OrderedLocusNames=YpsIP31758_4064;
OS   Yersinia pseudotuberculosis serotype O:1b (strain IP 31758).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=349747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP 31758;
RX   PubMed=17784789; DOI=10.1371/journal.pgen.0030142;
RA   Eppinger M., Rosovitz M.J., Fricke W.F., Rasko D.A., Kokorina G.,
RA   Fayolle C., Lindler L.E., Carniel E., Ravel J.;
RT   "The complete genome sequence of Yersinia pseudotuberculosis IP31758, the
RT   causative agent of Far East scarlet-like fever.";
RL   PLoS Genet. 3:1508-1523(2007).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the membrane.
CC       {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC       (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-Rule:MF_01300}.
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DR   EMBL; CP000720; ABS47569.1; -; Genomic_DNA.
DR   RefSeq; WP_012105938.1; NC_009708.1.
DR   AlphaFoldDB; A7FP30; -.
DR   SMR; A7FP30; -.
DR   EnsemblBacteria; ABS47569; ABS47569; YpsIP31758_4064.
DR   KEGG; ypi:YpsIP31758_4064; -.
DR   HOGENOM; CLU_019375_7_0_6; -.
DR   OMA; YLYIAVI; -.
DR   Proteomes; UP000002412; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006835; P:dicarboxylic acid transport; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR   PANTHER; PTHR42865; PTHR42865; 1.
DR   Pfam; PF00375; SDF; 1.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00713; NA_DICARBOXYL_SYMP_1; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Symport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..429
FT                   /note="C4-dicarboxylate transport protein"
FT                   /id="PRO_1000067474"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        184..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01300"
SQ   SEQUENCE   429 AA;  45526 MW;  29454320411680C3 CRC64;
     MKVSIFKTLY FQVLTAITIG VLLGHFYPEI GAQMKPLGDG FVKLIKMIIA PVIFCTVVTG
     IAGMESMKAV GRTGAIALLY FEIVSTLALL IGLVVVNVAQ PGVGMNIDPA TLDAKAVALY
     AEQASQQGII PFLLDIIPGS VVGAFASGNI LQVLLFAVLF GFALHRLGEK GQLIFNVIES
     FSRVIFGVIN MIMRLAPLGA FGAMAFTIGK YGVGSLVQLG QLILCFYLTC ILFVVLVLGT
     IAKFNGFNIF KFIRYIKEEL LIVLGTSSSE SVLPRMLDKM ENAGCKKSVV GLVIPTGYSF
     NLDGTSIYLT MAAVFIAQAT NTHMDIMHQV TLLVVLLLSS KGAAGVTGSG FIVLAATISA
     VGHLPLAGLA LILGIDRFMS EARALTNLVG NGVATIVVAK WCKQLDNDQL QAVLSNKVLP
     NVKNSVSVS