ID   ACT_EUPCR               Reviewed;         379 AA.
AC   P20360;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Actin, cytoplasmic;
OS   Euplotes crassus.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Hypotrichia; Euplotida; Euplotidae; Moneuplotes.
OX   NCBI_TaxID=5936;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2470096; DOI=10.1073/pnas.86.9.3252;
RA   Harper D.S., Jahn C.L.;
RT   "Differential use of termination codons in ciliated protozoa.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:3252-3256(1989).
CC   -!- FUNCTION: Actins are highly conserved proteins that are involved in
CC       various types of cell motility and are ubiquitously expressed in all
CC       eukaryotic cells.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
CC   -!- SIMILARITY: Belongs to the actin family. {ECO:0000305}.
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DR   EMBL; J04533; AAA29122.1; -; Genomic_DNA.
DR   PIR; A30309; A30309.
DR   AlphaFoldDB; P20360; -.
DR   SMR; P20360; -.
DR   PRIDE; P20360; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR020902; Actin/actin-like_CS.
DR   InterPro; IPR004001; Actin_CS.
DR   InterPro; IPR043129; ATPase_NBD.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   Pfam; PF00022; Actin; 1.
DR   PRINTS; PR00190; ACTIN.
DR   SMART; SM00268; ACTIN; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
DR   PROSITE; PS00406; ACTINS_1; 1.
DR   PROSITE; PS01132; ACTINS_ACT_LIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Cytoskeleton; Nucleotide-binding.
FT   CHAIN           1..379
FT                   /note="Actin, cytoplasmic"
FT                   /id="PRO_0000088939"
SQ   SEQUENCE   379 AA;  42624 MW;  A3AC0DFD3DE09D95 CRC64;
     MSEEENAKEA IVVDNGSGVV KAGFAGENQP CSVFPSVVAK PKTKQVIVGG AGNKDCFVGD
     ERQQKRGVCT LSYPIKSGMI KDWDGMQKIW DYTFYNELRI ETENHPVLLT EAPLNPKQNR
     ENMCRIMFEE YDFPSMYIQI QAVLSLYSAG RTTGIVVDSG DGVTHVVPIF EGYQIPHAIE
     KILLAGRDLT DYMCRILKDD DYHFETTAEK ETVRDIKEKL CYVADDYEAE LKKAGEGGEL
     EESYALPDGR PLKISTQRFQ CPEFLFQPDL GGRECKSVHQ LTYDSIMTCD LDVRKDLYAN
     IILSGGTTMF PGLGERLYKE MKDLAPQTMK VKVIASPDRK YAVWRGGSTL AKLSTFAGMW
     VTKEDYAEFG ESIVHRKCI