ID   DCTM_RHOCA              Reviewed;         440 AA.
AC   O07838;
DT   20-JAN-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=C4-dicarboxylate TRAP transporter large permease protein DctM {ECO:0000305};
GN   Name=dctM {ECO:0000303|PubMed:9287004};
OS   Rhodobacter capsulatus (Rhodopseudomonas capsulata).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=1061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBUNIT, SUBCELLULAR LOCATION,
RP   DISRUPTION PHENOTYPE, AND NOMENCLATURE.
RC   STRAIN=ATCC 33303 / B10;
RX   PubMed=9287004; DOI=10.1128/jb.179.17.5482-5493.1997;
RA   Forward J.A., Behrendt M.C., Wyborn N.R., Cross R., Kelly D.J.;
RT   "TRAP transporters: a new family of periplasmic solute transport systems
RT   encoded by the dctPQM genes of Rhodobacter capsulatus and by homologs in
RT   diverse gram-negative bacteria.";
RL   J. Bacteriol. 179:5482-5493(1997).
CC   -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC       transport system DctPQM involved in C4-dicarboxylates uptake.
CC       {ECO:0000269|PubMed:9287004}.
CC   -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC       protein DctP, and the two transmembrane proteins DctQ and DctM.
CC       {ECO:0000269|PubMed:9287004}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:9287004};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- DISRUPTION PHENOTYPE: Deletion mutant is unable to transport succinate,
CC       and does not grow on D-malate, L-malate, succinate or fumarate as the
CC       sole carbon source under aerobic conditions in the dark.
CC       {ECO:0000269|PubMed:9287004}.
CC   -!- SIMILARITY: Belongs to the TRAP transporter large permease family.
CC       {ECO:0000305}.
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DR   EMBL; X63974; CAA45387.1; -; Genomic_DNA.
DR   PIR; S19739; S19739.
DR   RefSeq; WP_013068719.1; NZ_VIBE01000005.1.
DR   AlphaFoldDB; O07838; -.
DR   TCDB; 2.A.56.1.1; the tripartite atp-independent periplasmic transporter (trap-t) family.
DR   GeneID; 31491814; -.
DR   OMA; IVVNMEV; -.
DR   GO; GO:0016021; C:integral component of membrane; IDA:CACAO.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010656; DctM.
DR   InterPro; IPR004681; TRAP_DctM.
DR   PANTHER; PTHR33362; PTHR33362; 1.
DR   Pfam; PF06808; DctM; 1.
DR   PIRSF; PIRSF006066; HI0050; 1.
DR   TIGRFAMs; TIGR00786; dctM; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..440
FT                   /note="C4-dicarboxylate TRAP transporter large permease
FT                   protein DctM"
FT                   /id="PRO_0000435379"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        230..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        318..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        349..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        410..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   440 AA;  46828 MW;  F28387EE0C96D065 CRC64;
     MSALIIFGLL IALMLTGMPI SISLGLTVLT FLFTMTQVPI DTVALKLFTG IEKFEIMAIP
     FFILAGNFLT HGGVAKRMIN FATAMVGHWH GGLGLAGVIA CALFAAVSGS SPATVVAIGS
     VILPAMVNQG FPKQFGAGVI TTSGALGILI PPSIVMVMYA VATSGMVVTG PDGQPVSSAS
     VGELFMAGVV PGLMLAGFLA FTTWNRARKF GYPRLEKASL RQRWTAFREA AWGLMLIVVV
     IGGIYAGIFT PTEAAAMSAV YAFFISVFVY KDLTLRDVPR VLLSSANMSA MLLYIITNAV
     LFSFLMAHEG IPQALGEWMV NAGLSWWMFL IIVNILLLAA GNFMEPSSIV LIMAPILFPV
     AVRLGIDPVH FGIMIVVNME VGMCHPPVGL NLYVASGITK MGITELTVAV WPWLLTMLAF
     LVLVTYVPAI SLALPNLLGM