ID   DCTN5_DICDI             Reviewed;         198 AA.
AC   Q54XU5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Dynactin subunit 5;
GN   Name=dynE; Synonyms=dctn5; ORFNames=DDB_G0278579;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBUNIT: Member of the pointed-end complex of the dynactin shoulder
CC       complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC       subunit 5 subfamily. {ECO:0000305}.
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DR   EMBL; AAFI02000023; EAL68462.1; -; Genomic_DNA.
DR   RefSeq; XP_642457.1; XM_637365.1.
DR   AlphaFoldDB; Q54XU5; -.
DR   SMR; Q54XU5; -.
DR   STRING; 44689.DDB0231396; -.
DR   PaxDb; Q54XU5; -.
DR   EnsemblProtists; EAL68462; EAL68462; DDB_G0278579.
DR   GeneID; 8621666; -.
DR   KEGG; ddi:DDB_G0278579; -.
DR   dictyBase; DDB_G0278579; dynE.
DR   eggNOG; KOG3121; Eukaryota.
DR   HOGENOM; CLU_088622_2_0_1; -.
DR   InParanoid; Q54XU5; -.
DR   OMA; IRIGQYV; -.
DR   PhylomeDB; Q54XU5; -.
DR   Reactome; R-DDI-6807878; COPI-mediated anterograde transport.
DR   PRO; PR:Q54XU5; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR   GO; GO:0044354; C:macropinosome; IDA:dictyBase.
DR   GO; GO:0001891; C:phagocytic cup; IDA:dictyBase.
DR   GO; GO:0005886; C:plasma membrane; IDA:dictyBase.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Dynactin subunit 5"
FT                   /id="PRO_0000330322"
FT   REGION          179..198
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  21627 MW;  42BB572061A2B57B CRC64;
     MQVQPKYFEK SQYIETLNGN KVSKSSILCG IMNIRLHGKT IIKPGVIVRG DLASVNIGRL
     SIISENTVIR PSSKKFKGSL VYFPQNIGDH VLVGEGCVIS AASIGSNVYI GNNCIISKRC
     ILKDCCIIAD NTILPPDTVV PPFTYYSGTP GVYKEDLPDC IEQFQKEYTT SLYESFLPNT
     PASKGLPSTP TKLQTTTT