ID   DCTN6_DANRE             Reviewed;         195 AA.
AC   Q502J7;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Dynactin subunit 6;
GN   Name=dctn6; ORFNames=zgc:112102;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Member of the pointed-end complex of the dynactin shoulder
CC       complex which contains dctn4, dctn5 and dctn6 subunits and Actr10.
CC       Within the complex dctn6 forms a heterodimer with dctn5. Interacts with
CC       plk1 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC       Chromosome, centromere, kinetochore {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC       subunit 6 subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC095670; AAH95670.1; -; mRNA.
DR   RefSeq; NP_001018487.1; NM_001020651.1.
DR   AlphaFoldDB; Q502J7; -.
DR   SMR; Q502J7; -.
DR   GeneID; 553678; -.
DR   KEGG; dre:553678; -.
DR   ZFIN; ZDB-GENE-050522-237; zgc:112102.
DR   InParanoid; Q502J7; -.
DR   OrthoDB; 1278795at2759; -.
DR   PhylomeDB; Q502J7; -.
DR   PRO; PR:Q502J7; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR   GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR   GO; GO:0070840; F:dynein complex binding; IBA:GO_Central.
DR   GO; GO:0007052; P:mitotic spindle organization; IBA:GO_Central.
DR   InterPro; IPR027777; DCTN6.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR13072; PTHR13072; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   2: Evidence at transcript level;
KW   Centromere; Chromosome; Cytoplasm; Cytoskeleton; Kinetochore;
KW   Reference proteome.
FT   CHAIN           1..195
FT                   /note="Dynactin subunit 6"
FT                   /id="PRO_0000327736"
SQ   SEQUENCE   195 AA;  20929 MW;  B21B74C796D86212 CRC64;
     MADPSAKQTG QKSVKIAAGA VVCVESDIRG DVTIGARTVV HPKARIIAEA GPIVIGEGNL
     IEEQALIINS FPENLLPNTD DVEPKPMIIG VNNVFEVGCV CQALKIGDNN VIESKADVGR
     SVMLTSGCIV GSCCQIHTCE VIPENTVIYG SECLRRVQTE RPQPQTLQLD FLMKILPNYH
     HLKKTVKSSG TPARS