ID   DCTN6_DICDI             Reviewed;         189 AA.
AC   Q54FM4;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Dynactin subunit 6;
GN   Name=dynF; Synonyms=dctn6; ORFNames=DDB_G0290757;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBUNIT: Member of the pointed-end complex of the dynactin shoulder
CC       complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC       subunit 6 subfamily. {ECO:0000305}.
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DR   EMBL; AAFI02000170; EAL62063.1; -; Genomic_DNA.
DR   RefSeq; XP_635567.1; XM_630475.1.
DR   AlphaFoldDB; Q54FM4; -.
DR   SMR; Q54FM4; -.
DR   STRING; 44689.DDB0233815; -.
DR   PaxDb; Q54FM4; -.
DR   EnsemblProtists; EAL62063; EAL62063; DDB_G0290757.
DR   GeneID; 8627813; -.
DR   KEGG; ddi:DDB_G0290757; -.
DR   dictyBase; DDB_G0290757; dynF.
DR   eggNOG; KOG4042; Eukaryota.
DR   HOGENOM; CLU_085418_0_0_1; -.
DR   InParanoid; Q54FM4; -.
DR   OMA; IECKSIG; -.
DR   PhylomeDB; Q54FM4; -.
DR   Reactome; R-DDI-6807878; COPI-mediated anterograde transport.
DR   PRO; PR:Q54FM4; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR   GO; GO:0070840; F:dynein complex binding; IBA:GO_Central.
DR   GO; GO:0007052; P:mitotic spindle organization; IBA:GO_Central.
DR   InterPro; IPR027777; DCTN6.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   PANTHER; PTHR13072; PTHR13072; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   SUPFAM; SSF51161; SSF51161; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..189
FT                   /note="Dynactin subunit 6"
FT                   /id="PRO_0000327741"
SQ   SEQUENCE   189 AA;  20438 MW;  F125E2EED0BF770B CRC64;
     MSTAPSPTIT SPTQTSPVVI NKSLICQDST VSNGVQIAIG TVLHPRSSII ISEGAGPIII
     GENNIIEELV QIVNKSPEPM IIGSNNLFEV GSYIECKSIG NGNVFEPKCK ILKNTIIKDQ
     CSIGAGCIVS EDKICENNTI IAQTQNSQIQ TTSTLPYDHH SSIHMTHLEL LHKSIPLFHT
     IKKTPILEK