DCTN6_NEMVE
ID DCTN6_NEMVE Reviewed; 184 AA.
AC A7SGU3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Dynactin subunit 6;
GN Name=dctn6; ORFNames=v1g170501;
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6;
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- SUBUNIT: Member of the pointed-end complex of the dynactin shoulder
CC complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the dynactin subunits 5/6 family. Dynactin
CC subunit 6 subfamily. {ECO:0000305}.
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DR EMBL; DS469655; EDO37040.1; -; Genomic_DNA.
DR RefSeq; XP_001629103.1; XM_001629053.1.
DR AlphaFoldDB; A7SGU3; -.
DR SMR; A7SGU3; -.
DR STRING; 45351.EDO37040; -.
DR EnsemblMetazoa; EDO37040; EDO37040; NEMVEDRAFT_v1g170501.
DR GeneID; 5508522; -.
DR KEGG; nve:5508522; -.
DR eggNOG; KOG4042; Eukaryota.
DR HOGENOM; CLU_085418_1_0_1; -.
DR InParanoid; A7SGU3; -.
DR OMA; PDYTVVY; -.
DR OrthoDB; 1278795at2759; -.
DR PhylomeDB; A7SGU3; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005869; C:dynactin complex; IBA:GO_Central.
DR GO; GO:0070840; F:dynein complex binding; IBA:GO_Central.
DR GO; GO:0007052; P:mitotic spindle organization; IBA:GO_Central.
DR InterPro; IPR027777; DCTN6.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR13072; PTHR13072; 1.
DR SUPFAM; SSF51161; SSF51161; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..184
FT /note="Dynactin subunit 6"
FT /id="PRO_0000327738"
SQ SEQUENCE 184 AA; 20153 MW; 7F28C1E80E9D0DA6 CRC64;
MAAARQTPRK LKIGAGSVVC QEAEIKGEVI IGSKTVVHPK ARIIAEAGPI IIGDNNLIEE
QVTIINPLQV EENEEVPPER IVMHIGCNNV FEVGSLCEAV KIGDNNILEA KSRVGRQTVL
SHGCVIGARC EVTSQETIPE NTVIYGQSCN RRVQAERPVP QSLQLDFLTK ILPNYHHMKK
SSRS